Zhao TQ - Search Results

1

Novel 3-(2,6,9-trisubstituted-9H-purine)-8-chalcone derivatives as potent anti-gastric cancer agents: Design, synthesis and structural optimization.

Zhao TQ, Zhao YD, Liu XY, Li ZH, Wang B, Zhang XH, Cao YQ, Ma LY, Liu HM. Zhao TQ, et al. Among authors: zhao yd. Eur J Med Chem. 2019 Jan 1;161:493-505. doi: 10.1016/j.ejmech.2018.10.058. Epub 2018 Oct 25. Eur J Med Chem. 2019. PMID: 30388465

2

Discovery of quinazoline derivatives as a novel class of potent and in vivo efficacious LSD1 inhibitors by drug repurposing.

Li Z, Qin T, Li Z, Zhao X, Zhang X, Zhao T, Yang N, Miao J, Ma J, Zhang Z. Li Z, et al. Eur J Med Chem. 2021 Dec 5;225:113778. doi: 10.1016/j.ejmech.2021.113778. Epub 2021 Aug 14. Eur J Med Chem. 2021. PMID: 34416665

3

Identification of thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents through the drug repurposing strategy.

Li ZH, Zhang J, Liu XQ, Geng PF, Ma JL, Wang B, Zhao TQ, Zhao B, Wei HM, Wang C, Fu DJ, Yu B, Liu HM. Li ZH, et al. Among authors: zhao b, zhao tq. Eur J Med Chem. 2017 Jul 28;135:204-212. doi: 10.1016/j.ejmech.2017.04.056. Epub 2017 Apr 22. Eur J Med Chem. 2017. PMID: 28456031

4

Design, synthesis and antiproliferative activity of thiazolo[5,4-d]pyrimidine derivatives through the atom replacement strategy.

Li ZH, Liu XQ, Geng PF, Zhang J, Ma JL, Wang B, Zhao TQ, Zhao B, Zhang XH, Yu B, Liu HM. Li ZH, et al. Among authors: zhao b, zhao tq. Eur J Med Chem. 2017 Sep 29;138:1034-1041. doi: 10.1016/j.ejmech.2017.07.039. Epub 2017 Jul 22. Eur J Med Chem. 2017. PMID: 28759876

5

Design, synthesis and preliminary antiproliferative activity studies of new diheteroaryl thioether derivatives.

Li ZH, Liu XQ, Zhao TQ, Geng PF, Liu Y, Zhao B, Guo WG, Yu B, Liu HM. Li ZH, et al. Among authors: zhao b, zhao tq. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4377-4382. doi: 10.1016/j.bmcl.2017.08.021. Epub 2017 Aug 18. Bioorg Med Chem Lett. 2017. PMID: 28838695

6

Design, synthesis and preliminary biological evaluation of new [1,2,3]triazolo[4,5-d]pyrimidine/thiourea hybrids as antiproliferative agents.

Li ZH, Liu XQ, Zhao TQ, Geng PF, Guo WG, Yu B, Liu HM. Li ZH, et al. Among authors: zhao tq. Eur J Med Chem. 2017 Oct 20;139:741-749. doi: 10.1016/j.ejmech.2017.08.042. Epub 2017 Aug 31. Eur J Med Chem. 2017. PMID: 28863355

7

Synthesis and preliminary antiproliferative activity of new pteridin-7(8H)-one derivatives.

Li ZH, Zhao TQ, Liu XQ, Zhao B, Wang C, Geng PF, Cao YQ, Fu DJ, Jiang LP, Yu B, Liu HM. Li ZH, et al. Among authors: zhao b, zhao tq. Eur J Med Chem. 2018 Jan 1;143:1396-1405. doi: 10.1016/j.ejmech.2017.10.037. Epub 2017 Oct 16. Eur J Med Chem. 2018. PMID: 29113745

8

Design, synthesis and preliminary biological evaluation of 5,8-dihydropteridine-6,7-diones that induce apoptosis and suppress cell migration.

Geng PF, Wang CC, Li ZH, Hu XN, Zhao TQ, Fu DJ, Zhao B, Yu B, Liu HM. Geng PF, et al. Among authors: zhao b, zhao tq. Eur J Med Chem. 2018 Jan 1;143:1959-1967. doi: 10.1016/j.ejmech.2017.11.009. Epub 2017 Nov 5. Eur J Med Chem. 2018. PMID: 29133051

9

Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing a thiosemicarbazide moiety.

Geng PF, Liu XQ, Zhao TQ, Wang CC, Li ZH, Zhang J, Wei HM, Hu B, Ma LY, Liu HM. Geng PF, et al. Among authors: zhao tq. Eur J Med Chem. 2018 Feb 25;146:147-156. doi: 10.1016/j.ejmech.2018.01.031. Epub 2018 Jan 17. Eur J Med Chem. 2018. PMID: 29407946

10

Discovery of 6-chloro-2-(propylthio)-8,9-dihydro-7H-purines containing a carboxamide moiety as potential selective anti-lung cancer agents.

Zhao TQ, Zhao YD, Liu XY, Wang B, Li ZH, He ZX, Zhang XH, Liang JJ, Ma LY, Liu HM. Zhao TQ, et al. Among authors: zhao yd. Eur J Med Chem. 2018 May 10;151:327-338. doi: 10.1016/j.ejmech.2018.03.084. Epub 2018 Apr 3. Eur J Med Chem. 2018. PMID: 29635165

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