Pentelute BL - Search Results

1

Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.

Bergmann S, Lawler SE, Qu Y, Fadzen CM, Wolfe JM, Regan MS, Pentelute BL, Agar NYR, Cho CF. Bergmann S, et al. Among authors: pentelute bl. Nat Protoc. 2018 Dec;13(12):2827-2843. doi: 10.1038/s41596-018-0066-x. Nat Protoc. 2018. PMID: 30382243 Free PMC article.

2

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.

Cho CF, Wolfe JM, Fadzen CM, Calligaris D, Hornburg K, Chiocca EA, Agar NYR, Pentelute BL, Lawler SE. Cho CF, et al. Among authors: pentelute bl. Nat Commun. 2017 Jun 6;8:15623. doi: 10.1038/ncomms15623. Nat Commun. 2017. PMID: 28585535 Free PMC article.

3

Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier.

Fadzen CM, Wolfe JM, Cho CF, Chiocca EA, Lawler SE, Pentelute BL. Fadzen CM, et al. Among authors: pentelute bl. J Am Chem Soc. 2017 Nov 8;139(44):15628-15631. doi: 10.1021/jacs.7b09790. Epub 2017 Oct 30. J Am Chem Soc. 2017. PMID: 28992407 Free PMC article.

4

Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides.

Wolfe JM, Fadzen CM, Holden RL, Yao M, Hanson GJ, Pentelute BL. Wolfe JM, et al. Among authors: pentelute bl. Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4756-4759. doi: 10.1002/anie.201801167. Epub 2018 Mar 14. Angew Chem Int Ed Engl. 2018. PMID: 29479836 Free PMC article.

5

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery.

Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. Wolfe JM, et al. Among authors: pentelute bl. ACS Cent Sci. 2018 Apr 25;4(4):512-520. doi: 10.1021/acscentsci.8b00098. Epub 2018 Apr 5. ACS Cent Sci. 2018. PMID: 29721534 Free PMC article.

6

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins.

Cohen DT, Zhang C, Fadzen CM, Mijalis AJ, Hie L, Johnson KD, Shriver Z, Plante O, Miller SJ, Buchwald SL, Pentelute BL. Cohen DT, et al. Among authors: pentelute bl. Nat Chem. 2019 Jan;11(1):78-85. doi: 10.1038/s41557-018-0154-0. Epub 2018 Nov 5. Nat Chem. 2019. PMID: 30397320 Free PMC article.

7

Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy.

Fadzen CM, Holden RL, Wolfe JM, Choo ZN, Schissel CK, Yao M, Hanson GJ, Pentelute BL. Fadzen CM, et al. Among authors: pentelute bl. Biochemistry. 2019 Sep 24;58(38):3980-3989. doi: 10.1021/acs.biochem.9b00413. Epub 2019 Sep 6. Biochemistry. 2019. PMID: 31450889

8

A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain.

Fadzen CM, Wolfe JM, Zhou W, Cho CF, von Spreckelsen N, Hutchinson KT, Lee YC, Chiocca EA, Lawler SE, Yilmaz OH, Lippard SJ, Pentelute BL. Fadzen CM, et al. Among authors: pentelute bl. J Med Chem. 2020 Jul 9;63(13):6741-6747. doi: 10.1021/acs.jmedchem.0c00022. Epub 2020 Jun 26. J Med Chem. 2020. PMID: 32410451 Free PMC article.

9

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican.

von Spreckelsen N, Fadzen CM, Hartrampf N, Ghotmi Y, Wolfe JM, Dubey S, Yang BY, Kijewski MF, Wang S, Farquhar C, Bergmann S, Zdioruk M, Wasserburg JR, Scott B, Murrell E, Bononi FC, Luyt LG, DiCarli M, Lamfers MLM, Ligon KL, Chiocca EA, Viapiano MS, Pentelute BL, Lawler SE, Cho CF. von Spreckelsen N, et al. Among authors: pentelute bl. Adv Ther (Weinh). 2021 Apr;4(4):2000244. doi: 10.1002/adtp.202000244. Epub 2021 Jan 20. Adv Ther (Weinh). 2021. PMID: 33997269 Free PMC article.

10

Deep learning to design nuclear-targeting abiotic miniproteins.

Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu CL, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Schissel CK, et al. Among authors: pentelute bl. Nat Chem. 2021 Oct;13(10):992-1000. doi: 10.1038/s41557-021-00766-3. Epub 2021 Aug 9. Nat Chem. 2021. PMID: 34373596 Free PMC article.

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