Lawler SE - Search Results

1

Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.

Bergmann S, Lawler SE, Qu Y, Fadzen CM, Wolfe JM, Regan MS, Pentelute BL, Agar NYR, Cho CF. Bergmann S, et al. Among authors: lawler se. Nat Protoc. 2018 Dec;13(12):2827-2843. doi: 10.1038/s41596-018-0066-x. Nat Protoc. 2018. PMID: 30382243 Free PMC article.

2

BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma.

Speranza MC, Nowicki MO, Behera P, Cho CF, Chiocca EA, Lawler SE. Speranza MC, et al. Among authors: lawler se. Sci Rep. 2016 Feb 5;6:20189. doi: 10.1038/srep20189. Sci Rep. 2016. PMID: 26846842 Free PMC article.

3

Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.

Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE. Cho CF, et al. Among authors: lawler se. ACS Comb Sci. 2016 Jun 13;18(6):271-8. doi: 10.1021/acscombsci.5b00180. Epub 2016 May 23. ACS Comb Sci. 2016. PMID: 27124678 Free PMC article.

4

Oncolytic Viruses in Cancer Treatment: A Review.

Lawler SE, Speranza MC, Cho CF, Chiocca EA. Lawler SE, et al. JAMA Oncol. 2017 Jun 1;3(6):841-849. doi: 10.1001/jamaoncol.2016.2064. JAMA Oncol. 2017. PMID: 27441411 Review.

5

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.

Cho CF, Wolfe JM, Fadzen CM, Calligaris D, Hornburg K, Chiocca EA, Agar NYR, Pentelute BL, Lawler SE. Cho CF, et al. Among authors: lawler se. Nat Commun. 2017 Jun 6;8:15623. doi: 10.1038/ncomms15623. Nat Commun. 2017. PMID: 28585535 Free PMC article.

6

Perfluoroarene-Based Peptide Macrocycles to Enhance Penetration Across the Blood-Brain Barrier.

Fadzen CM, Wolfe JM, Cho CF, Chiocca EA, Lawler SE, Pentelute BL. Fadzen CM, et al. Among authors: lawler se. J Am Chem Soc. 2017 Nov 8;139(44):15628-15631. doi: 10.1021/jacs.7b09790. Epub 2017 Oct 30. J Am Chem Soc. 2017. PMID: 28992407 Free PMC article.

7

Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data.

Abdelmoula WM, Regan MS, Lopez BGC, Randall EC, Lawler S, Mladek AC, Nowicki MO, Marin BM, Agar JN, Swanson KR, Kapur T, Sarkaria JN, Wells W, Agar NYR. Abdelmoula WM, et al. Anal Chem. 2019 May 7;91(9):6206-6216. doi: 10.1021/acs.analchem.9b00854. Epub 2019 Apr 22. Anal Chem. 2019. PMID: 30932478 Free PMC article.

8

A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain.

Fadzen CM, Wolfe JM, Zhou W, Cho CF, von Spreckelsen N, Hutchinson KT, Lee YC, Chiocca EA, Lawler SE, Yilmaz OH, Lippard SJ, Pentelute BL. Fadzen CM, et al. Among authors: lawler se. J Med Chem. 2020 Jul 9;63(13):6741-6747. doi: 10.1021/acs.jmedchem.0c00022. Epub 2020 Jun 26. J Med Chem. 2020. PMID: 32410451 Free PMC article.

9

Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican.

von Spreckelsen N, Fadzen CM, Hartrampf N, Ghotmi Y, Wolfe JM, Dubey S, Yang BY, Kijewski MF, Wang S, Farquhar C, Bergmann S, Zdioruk M, Wasserburg JR, Scott B, Murrell E, Bononi FC, Luyt LG, DiCarli M, Lamfers MLM, Ligon KL, Chiocca EA, Viapiano MS, Pentelute BL, Lawler SE, Cho CF. von Spreckelsen N, et al. Among authors: lawler se. Adv Ther (Weinh). 2021 Apr;4(4):2000244. doi: 10.1002/adtp.202000244. Epub 2021 Jan 20. Adv Ther (Weinh). 2021. PMID: 33997269 Free PMC article.

10

A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood-Brain Barrier Permeability and Targets Glioblastoma.

Cho CF, Farquhar CE, Fadzen CM, Scott B, Zhuang P, von Spreckelsen N, Loas A, Hartrampf N, Pentelute BL, Lawler SE. Cho CF, et al. Among authors: lawler se. Cancers (Basel). 2022 Apr 28;14(9):2207. doi: 10.3390/cancers14092207. Cancers (Basel). 2022. PMID: 35565337 Free PMC article.

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