Radu RA - Search Results

1

An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4^-/- Mice.

McClements ME, Barnard AR, Singh MS, Charbel Issa P, Jiang Z, Radu RA, MacLaren RE. McClements ME, et al. Among authors: radu ra. Hum Gene Ther. 2019 May;30(5):590-600. doi: 10.1089/hum.2018.156. Epub 2018 Dec 24. Hum Gene Ther. 2019. PMID: 30381971 Free PMC article.

2

Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration.

Radu RA, Mata NL, Bagla A, Travis GH. Radu RA, et al. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5928-33. doi: 10.1073/pnas.0308302101. Epub 2004 Apr 5. Proc Natl Acad Sci U S A. 2004. PMID: 15067110 Free PMC article.

3

Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation.

Radu RA, Yuan Q, Hu J, Peng JH, Lloyd M, Nusinowitz S, Bok D, Travis GH. Radu RA, et al. Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3821-9. doi: 10.1167/iovs.07-1470. Epub 2008 May 30. Invest Ophthalmol Vis Sci. 2008. PMID: 18515570 Free PMC article.

4

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.

Radu RA, Hu J, Yuan Q, Welch DL, Makshanoff J, Lloyd M, McMullen S, Travis GH, Bok D. Radu RA, et al. J Biol Chem. 2011 May 27;286(21):18593-601. doi: 10.1074/jbc.M110.191866. Epub 2011 Apr 4. J Biol Chem. 2011. PMID: 21464132 Free PMC article.

5

Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.

Charbel Issa P, Barnard AR, Singh MS, Carter E, Jiang Z, Radu RA, Schraermeyer U, MacLaren RE. Charbel Issa P, et al. Among authors: radu ra. Invest Ophthalmol Vis Sci. 2013 Aug 19;54(8):5602-12. doi: 10.1167/iovs.13-11688. Invest Ophthalmol Vis Sci. 2013. PMID: 23761084 Free PMC article.

6

Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.

Radu RA, Hu J, Jiang Z, Bok D. Radu RA, et al. J Biol Chem. 2014 Mar 28;289(13):9113-20. doi: 10.1074/jbc.M114.548669. Epub 2014 Feb 18. J Biol Chem. 2014. PMID: 24550392 Free PMC article.

7

Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.

Nociari MM, Lehmann GL, Perez Bay AE, Radu RA, Jiang Z, Goicochea S, Schreiner R, Warren JD, Shan J, Adam de Beaumais S, Ménand M, Sollogoub M, Maxfield FR, Rodriguez-Boulan E. Nociari MM, et al. Among authors: radu ra. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1402-8. doi: 10.1073/pnas.1400530111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706818 Free PMC article.

8

Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium.

Toops KA, Tan LX, Jiang Z, Radu RA, Lakkaraju A. Toops KA, et al. Among authors: radu ra. Mol Biol Cell. 2015 Jan 1;26(1):1-14. doi: 10.1091/mbc.E14-05-1028. Epub 2014 Nov 5. Mol Biol Cell. 2015. PMID: 25378587 Free PMC article.

9

Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study.

Müller PL, Gliem M, Mangold E, Bolz HJ, Finger RP, McGuinness M, Betz C, Jiang Z, Weber BH, MacLaren RE, Holz FG, Radu RA, Charbel Issa P. Müller PL, et al. Among authors: radu ra. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8179-86. doi: 10.1167/iovs.15-17629. Invest Ophthalmol Vis Sci. 2015. PMID: 26720470 Free PMC article.

10

Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.

Lenis TL, Sarfare S, Jiang Z, Lloyd MB, Bok D, Radu RA. Lenis TL, et al. Among authors: radu ra. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3987-3992. doi: 10.1073/pnas.1620299114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348233 Free PMC article.

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