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Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.
Bulman CA, Bidlow CM, Lustigman S, Cho-Ngwa F, Williams D, Rascón AA Jr, Tricoche N, Samje M, Bell A, Suzuki B, Lim KC, Supakorndej N, Supakorndej P, Wolfe AR, Knudsen GM, Chen S, Wilson C, Ang KH, Arkin M, Gut J, Franklin C, Marcellino C, McKerrow JH, Debnath A, Sakanari JA. Bulman CA, et al. Among authors: sakanari ja. PLoS Negl Trop Dis. 2015 Feb 20;9(2):e0003534. doi: 10.1371/journal.pntd.0003534. eCollection 2015 Feb. PLoS Negl Trop Dis. 2015. PMID: 25700363 Free PMC article.
Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.
Lin Y, Jung H, Bulman CA, Ng J, Vinck R, O'Beirne C, Zhong S, Moser MS, Tricoche N, Peguero R, Li RW, Urban JF Jr, Le Pape P, Pagniez F, Moretto M, Weil T, Lustigman S, Cariou K, Mitreva M, Sakanari JA, Gasser G. Lin Y, et al. Among authors: sakanari ja. J Med Chem. 2023 Dec 14;66(23):15867-15882. doi: 10.1021/acs.jmedchem.3c01333. Epub 2023 Nov 27. J Med Chem. 2023. PMID: 38009931
Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics.
Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman CA, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley PJ, Tseng CC, Greig IR, Sakanari J, Wildman SA, Aroian R, Janetka JW, Mitreva M. Tyagi R, et al. ACS Infect Dis. 2018 Jul 13;4(7):1130-1145. doi: 10.1021/acsinfecdis.8b00090. Epub 2018 May 14. ACS Infect Dis. 2018. PMID: 29718656 Free PMC article.
Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.
Voronin D, Tricoche N, Jawahar S, Shlossman M, Bulman CA, Fischer C, Suderman MT, Sakanari JA, Lustigman S. Voronin D, et al. Among authors: sakanari ja. PLoS Negl Trop Dis. 2019 Jan 17;13(1):e0007108. doi: 10.1371/journal.pntd.0007108. eCollection 2019 Jan. PLoS Negl Trop Dis. 2019. PMID: 30653499 Free PMC article.
66 results