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Page 1
Safe CRISPR: Challenges and Possible Solutions.
Pineda M, Lear A, Collins JP, Kiani S. Pineda M, et al. Among authors: kiani s. Trends Biotechnol. 2019 Apr;37(4):389-401. doi: 10.1016/j.tibtech.2018.09.010. Epub 2018 Oct 21. Trends Biotechnol. 2019. PMID: 30352704 Review.
Engineered CRISPR Systems for Next Generation Gene Therapies.
Pineda M, Moghadam F, Ebrahimkhani MR, Kiani S. Pineda M, et al. Among authors: kiani s. ACS Synth Biol. 2017 Sep 15;6(9):1614-1626. doi: 10.1021/acssynbio.7b00011. Epub 2017 Jun 7. ACS Synth Biol. 2017. PMID: 28558198 Review.
Synthetic immunomodulation with a CRISPR super-repressor in vivo.
Moghadam F, LeGraw R, Velazquez JJ, Yeo NC, Xu C, Park J, Chavez A, Ebrahimkhani MR, Kiani S. Moghadam F, et al. Among authors: kiani s. Nat Cell Biol. 2020 Sep;22(9):1143-1154. doi: 10.1038/s41556-020-0563-3. Epub 2020 Sep 3. Nat Cell Biol. 2020. PMID: 32884147 Free PMC article.
An enhanced CRISPR repressor for targeted mammalian gene regulation.
Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM. Yeo NC, et al. Among authors: kiani s. Nat Methods. 2018 Aug;15(8):611-616. doi: 10.1038/s41592-018-0048-5. Epub 2018 Jul 16. Nat Methods. 2018. PMID: 30013045 Free PMC article.
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Among authors: kiani s. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Multicellular Systems to Translate Somatic Cell Genome Editors to Humans.
Hernandez-Gordillo V, Casolaro TC, Ebrahimkhani MR, Kiani S. Hernandez-Gordillo V, et al. Among authors: kiani s. Curr Opin Biomed Eng. 2020 Dec;16:72-81. doi: 10.1016/j.cobme.2020.100249. Epub 2020 Oct 10. Curr Opin Biomed Eng. 2020. PMID: 33718690 Free PMC article.
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