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Small Molecule Condensin Inhibitors.
Zhao H, Petrushenko ZM, Walker JK, Baudry J, Zgurskaya HI, Rybenkov VV. Zhao H, et al. Among authors: walker jk. ACS Infect Dis. 2018 Dec 14;4(12):1737-1745. doi: 10.1021/acsinfecdis.8b00222. Epub 2018 Oct 22. ACS Infect Dis. 2018. PMID: 30346684 Free PMC article.
Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold.
Green AT, Moniruzzaman M, Cooper CJ, Walker JK, Smith JC, Parks JM, Zgurskaya HI. Green AT, et al. Among authors: walker jk. Biochim Biophys Acta Gen Subj. 2020 Jun;1864(6):129546. doi: 10.1016/j.bbagen.2020.129546. Epub 2020 Feb 4. Biochim Biophys Acta Gen Subj. 2020. PMID: 32032658 Free PMC article.
Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa.
Mehla J, Malloci G, Mansbach R, López CA, Tsivkovski R, Haynes K, Leus IV, Grindstaff SB, Cascella RH, D'Cunha N, Herndon L, Hengartner NW, Margiotta E, Atzori A, Vargiu AV, Manrique PD, Walker JK, Lomovskaya O, Ruggerone P, Gnanakaran S, Rybenkov VV, Zgurskaya HI. Mehla J, et al. Among authors: walker jk. mBio. 2021 Jan 19;12(1):e02785-20. doi: 10.1128/mBio.02785-20. mBio. 2021. PMID: 33468691 Free PMC article.
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides.
D'Cunha N, Moniruzzaman M, Haynes K, Malloci G, Cooper CJ, Margiotta E, Vargiu AV, Uddin MR, Leus IV, Cao F, Parks JM, Rybenkov VV, Ruggerone P, Zgurskaya HI, Walker JK. D'Cunha N, et al. Among authors: walker jk. ACS Infect Dis. 2021 Sep 10;7(9):2650-2665. doi: 10.1021/acsinfecdis.1c00100. Epub 2021 Aug 11. ACS Infect Dis. 2021. PMID: 34379382 Free PMC article.
188 results