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Page 1
Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.
Haddad JF, Yang Y, Takahashi YH, Joshi M, Chaudhary N, Woodfin AR, Benyoucef A, Yeung S, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. Haddad JF, et al. Among authors: skiniotis g. Structure. 2018 Dec 4;26(12):1594-1603.e4. doi: 10.1016/j.str.2018.08.004. Epub 2018 Sep 27. Structure. 2018. PMID: 30270175 Free article.
Insights into distinct signaling profiles of the µOR activated by diverse agonists.
Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, Kobilka BK, Skiniotis G. Qu Q, et al. Among authors: skiniotis g. Nat Chem Biol. 2023 Apr;19(4):423-430. doi: 10.1038/s41589-022-01208-y. Epub 2022 Nov 21. Nat Chem Biol. 2023. PMID: 36411392 Free PMC article.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, Slocum ST, Eans SO, Cameron MD, Al-Hasani R, Pan YX, Roth BL, McLaughlin JP, Skiniotis G, Katritch V, Kobilka BK, Majumdar S. Faouzi A, et al. Among authors: skiniotis g. Nature. 2023 Jan;613(7945):767-774. doi: 10.1038/s41586-022-05588-y. Epub 2022 Nov 30. Nature. 2023. PMID: 36450356 Free PMC article.
Time-resolved cryo-EM of G protein activation by a GPCR.
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi M, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G. Papasergi-Scott MM, et al. Among authors: skiniotis g. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533387. doi: 10.1101/2023.03.20.533387. bioRxiv. 2023. Update in: Nature. 2024 May;629(8014):1182-1191. doi: 10.1038/s41586-024-07153-1. PMID: 36993214 Free PMC article. Updated. Preprint.
Assembling a COMPASS.
Couture JF, Skiniotis G. Couture JF, et al. Among authors: skiniotis g. Epigenetics. 2013 Apr;8(4):349-54. doi: 10.4161/epi.24177. Epub 2013 Mar 7. Epigenetics. 2013. PMID: 23470558 Free PMC article.
Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation.
Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A. Thornton JL, et al. Among authors: skiniotis g. Genes Dev. 2014 Jan 15;28(2):115-20. doi: 10.1101/gad.232215.113. Epub 2014 Jan 8. Genes Dev. 2014. PMID: 24402317 Free PMC article.
Molecular basis for DPY-30 association to COMPASS-like and NURF complexes.
Tremblay V, Zhang P, Chaturvedi CP, Thornton J, Brunzelle JS, Skiniotis G, Shilatifard A, Brand M, Couture JF. Tremblay V, et al. Among authors: skiniotis g. Structure. 2014 Dec 2;22(12):1821-1830. doi: 10.1016/j.str.2014.10.002. Epub 2014 Nov 20. Structure. 2014. PMID: 25456412 Free PMC article.
A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. Zhang P, et al. Among authors: skiniotis g. Genes Dev. 2015 Jan 15;29(2):123-8. doi: 10.1101/gad.254870.114. Genes Dev. 2015. PMID: 25593305 Free PMC article.
126 results