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Page 1
Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS.
Iannitti T, Scarrott JM, Likhite S, Coldicott IRP, Lewis KE, Heath PR, Higginbottom A, Myszczynska MA, Milo M, Hautbergue GM, Meyer K, Kaspar BK, Ferraiuolo L, Shaw PJ, Azzouz M. Iannitti T, et al. Among authors: scarrott jm. Mol Ther Nucleic Acids. 2018 Sep 7;12:75-88. doi: 10.1016/j.omtn.2018.04.015. Epub 2018 May 3. Mol Ther Nucleic Acids. 2018. PMID: 30195799 Free PMC article.
Current developments in gene therapy for amyotrophic lateral sclerosis.
Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ, Azzouz M. Scarrott JM, et al. Expert Opin Biol Ther. 2015 Jul;15(7):935-47. doi: 10.1517/14712598.2015.1044894. Epub 2015 May 10. Expert Opin Biol Ther. 2015. PMID: 25959569 Free article. Review.
Gene Therapy in the Nervous System: Failures and Successes.
Chandran JS, Scarrott JM, Shaw PJ, Azzouz M. Chandran JS, et al. Among authors: scarrott jm. Adv Exp Med Biol. 2017;1007:241-257. doi: 10.1007/978-3-319-60733-7_13. Adv Exp Med Biol. 2017. PMID: 28840561 Review.
Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking.
Behne R, Teinert J, Wimmer M, D'Amore A, Davies AK, Scarrott JM, Eberhardt K, Brechmann B, Chen IP, Buttermore ED, Barrett L, Dwyer S, Chen T, Hirst J, Wiesener A, Segal D, Martinuzzi A, Duarte ST, Bennett JT, Bourinaris T, Houlden H, Roubertie A, Santorelli FM, Robinson M, Azzouz M, Lipton JO, Borner GHH, Sahin M, Ebrahimi-Fakhari D. Behne R, et al. Among authors: scarrott jm. Hum Mol Genet. 2020 Jan 15;29(2):320-334. doi: 10.1093/hmg/ddz310. Hum Mol Genet. 2020. PMID: 31915823 Free PMC article.
Production of trimeric SARS-CoV-2 spike protein by CHO cells for serological COVID-19 testing.
Johari YB, Jaffé SRP, Scarrott JM, Johnson AO, Mozzanino T, Pohle TH, Maisuria S, Bhayat-Cammack A, Lambiase G, Brown AJ, Tee KL, Jackson PJ, Wong TS, Dickman MJ, Sargur RB, James DC. Johari YB, et al. Among authors: scarrott jm. Biotechnol Bioeng. 2021 Feb;118(2):1013-1021. doi: 10.1002/bit.27615. Epub 2020 Nov 11. Biotechnol Bioeng. 2021. PMID: 33128388 Free article.
Pre-clinical development of AP4B1 gene replacement therapy for hereditary spastic paraplegia type 47.
Wiseman JP, Scarrott JM, Alves-Cruzeiro J, Saffari A, Böger C, Karyka E, Dawes E, Davies AK, Marchi PM, Graves E, Fernandes F, Yang ZL, Coldicott I, Hirst J, Webster CP, Highley JR, Hackett N, Angyal A, Silva T, Higginbottom A, Shaw PJ, Ferraiuolo L, Ebrahimi-Fakhari D, Azzouz M. Wiseman JP, et al. Among authors: scarrott jm. EMBO Mol Med. 2024 Oct 2. doi: 10.1038/s44321-024-00148-5. Online ahead of print. EMBO Mol Med. 2024. PMID: 39358605 Free article.