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Page 1
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Sołdacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, … See abstract for full author list ➔ Lyu YX, et al. Among authors: gruhn jr. Aging (Albany NY). 2024 Oct 16;16(20):12955-12976. doi: 10.18632/aging.206135. Epub 2024 Oct 16. Aging (Albany NY). 2024. PMID: 39418098 Free PMC article. Review.
Cell-free fetal DNA for genetic evaluation in Copenhagen Pregnancy Loss Study (COPL): a prospective cohort study.
Schlaikjær Hartwig T, Ambye L, Gruhn JR, Petersen JF, Wrønding T, Amato L, Chi-Ho Chan A, Ji B, Bro-Jørgensen MH, Werge L, Petersen MMBS, Brinkmann C, Ribberholt JB, Dunø M, Bache I, Herrgård MJ, Jørgensen FS, Hoffmann ER, Nielsen HS; COPL consortium. Schlaikjær Hartwig T, et al. Among authors: gruhn jr. Lancet. 2023 Mar 4;401(10378):762-771. doi: 10.1016/S0140-6736(22)02610-1. Epub 2023 Feb 2. Lancet. 2023. PMID: 36739882
Origins and mechanisms leading to aneuploidy in human eggs.
Wartosch L, Schindler K, Schuh M, Gruhn JR, Hoffmann ER, McCoy RC, Xing J. Wartosch L, et al. Among authors: gruhn jr. Prenat Diagn. 2021 Apr;41(5):620-630. doi: 10.1002/pd.5927. Epub 2021 Mar 22. Prenat Diagn. 2021. PMID: 33860956 Free PMC article.
Failure to recombine is a common feature of human oogenesis.
Hassold T, Maylor-Hagen H, Wood A, Gruhn J, Hoffmann E, Broman KW, Hunt P. Hassold T, et al. Among authors: gruhn j. Am J Hum Genet. 2021 Jan 7;108(1):16-24. doi: 10.1016/j.ajhg.2020.11.010. Epub 2020 Dec 10. Am J Hum Genet. 2021. PMID: 33306948 Free PMC article.
Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs.
Zielinska AP, Bellou E, Sharma N, Frombach AS, Seres KB, Gruhn JR, Blayney M, Eckel H, Moltrecht R, Elder K, Hoffmann ER, Schuh M. Zielinska AP, et al. Among authors: gruhn jr. Curr Biol. 2019 Nov 18;29(22):3749-3765.e7. doi: 10.1016/j.cub.2019.09.006. Epub 2019 Oct 31. Curr Biol. 2019. PMID: 31679939 Free PMC article.
Chromosome errors in human eggs shape natural fertility over reproductive life span.
Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, Nikiforov D, Chan AC, Newnham LJ, Vogel I, Scarica C, Krapchev M, Taylor D, Kristensen SG, Cheng J, Ernst E, Bjørn AB, Colmorn LB, Blayney M, Elder K, Liss J, Hartshorne G, Grøndahl ML, Rienzi L, Ubaldi F, McCoy R, Lukaszuk K, Andersen CY, Schuh M, Hoffmann ER. Gruhn JR, et al. Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321. Science. 2019. PMID: 31604276 Free PMC article.
In Vitro Maturation and Culture of Human Oocytes.
Gruhn JR, Kristensen SG, Andersen CY, Hoffmann ER. Gruhn JR, et al. Methods Mol Biol. 2018;1818:23-30. doi: 10.1007/978-1-4939-8603-3_3. Methods Mol Biol. 2018. PMID: 29961251
66 results