Lui GYL - Search Results

1

CDK12: an emerging therapeutic target for cancer.

Lui GYL, Grandori C, Kemp CJ. Lui GYL, et al. J Clin Pathol. 2018 Nov;71(11):957-962. doi: 10.1136/jclinpath-2018-205356. Epub 2018 Aug 13. J Clin Pathol. 2018. PMID: 30104286 Free PMC article. Review.

2

BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer.

Lui GYL, Shaw R, Schaub FX, Stork IN, Gurley KE, Bridgwater C, Diaz RL, Rosati R, Swan HA, Ince TA, Harding TC, Gadi VK, Goff BA, Kemp CJ, Swisher EM, Grandori C. Lui GYL, et al. EBioMedicine. 2020 Oct;60:102988. doi: 10.1016/j.ebiom.2020.102988. Epub 2020 Sep 11. EBioMedicine. 2020. PMID: 32927276 Free PMC article.

3

Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma.

Shigeta S, Lui GYL, Shaw R, Moser R, Gurley KE, Durenberger G, Rosati R, Diaz RL, Ince TA, Swisher EM, Grandori C, Kemp CJ. Shigeta S, et al. Among authors: lui gyl. Mol Cancer Ther. 2021 Apr;20(4):691-703. doi: 10.1158/1535-7163.MCT-20-0809. Epub 2021 Jan 28. Mol Cancer Ther. 2021. PMID: 33509905 Free PMC article.

4

Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer.

Cao J, Zhu Z, Wang H, Nichols TC, Lui GYL, Deng S, Rejto PA, VanArsdale T, Hardwick JS, Weinrich SL, Wei P. Cao J, et al. Among authors: lui gyl. Oncogene. 2019 May;38(21):4125-4141. doi: 10.1038/s41388-019-0708-7. Epub 2019 Jan 30. Oncogene. 2019. PMID: 30700828

5

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.

Dixon KM, Lui GY, Kovacevic Z, Zhang D, Yao M, Chen Z, Dong Q, Assinder SJ, Richardson DR. Dixon KM, et al. Br J Cancer. 2013 Feb 5;108(2):409-19. doi: 10.1038/bjc.2012.582. Epub 2013 Jan 3. Br J Cancer. 2013. PMID: 23287991 Free PMC article.

6

Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo.

Ford SJ, Obeidy P, Lovejoy DB, Bedford M, Nichols L, Chadwick C, Tucker O, Lui GY, Kalinowski DS, Jansson PJ, Iqbal TH, Alderson D, Richardson DR, Tselepis C. Ford SJ, et al. Br J Pharmacol. 2013 Mar;168(6):1316-28. doi: 10.1111/bph.12045. Br J Pharmacol. 2013. PMID: 23126308 Free PMC article.

7

Targeting cancer by binding iron: Dissecting cellular signaling pathways.

Lui GY, Kovacevic Z, Richardson V, Merlot AM, Kalinowski DS, Richardson DR. Lui GY, et al. Oncotarget. 2015 Aug 7;6(22):18748-79. doi: 10.18632/oncotarget.4349. Oncotarget. 2015. PMID: 26125440 Free PMC article. Review.

8

Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells.

Beaumont KA, Hill DS, Daignault SM, Lui GYL, Sharp DM, Gabrielli B, Weninger W, Haass NK. Beaumont KA, et al. Among authors: lui gyl. J Invest Dermatol. 2016 Jul;136(7):1479-1489. doi: 10.1016/j.jid.2016.02.805. Epub 2016 Mar 10. J Invest Dermatol. 2016. PMID: 26970356 Free article.

9

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action.

Lui GY, Obeidy P, Ford SJ, Tselepis C, Sharp DM, Jansson PJ, Kalinowski DS, Kovacevic Z, Lovejoy DB, Richardson DR. Lui GY, et al. Mol Pharmacol. 2013 Jan;83(1):179-90. doi: 10.1124/mol.112.081893. Epub 2012 Oct 16. Mol Pharmacol. 2013. PMID: 23074173

10

The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.

Kovacevic Z, Chikhani S, Lui GY, Sivagurunathan S, Richardson DR. Kovacevic Z, et al. Antioxid Redox Signal. 2013 Mar 10;18(8):874-87. doi: 10.1089/ars.2011.4273. Epub 2012 May 8. Antioxid Redox Signal. 2013. PMID: 22462691

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