Heinbockel L - Search Results

1

Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease.

Heinbockel L, Marwitz S, Schromm AB, Watz H, Kugler C, Ammerpohl O, Schnepf K, Rabe KF, Droemann D, Goldmann T. Heinbockel L, et al. Int J Chron Obstruct Pulmon Dis. 2018 Jul 26;13:2255-2259. doi: 10.2147/COPD.S161958. eCollection 2018. Int J Chron Obstruct Pulmon Dis. 2018. PMID: 30100715 Free PMC article.

2

Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression.

Marwitz S, Heinbockel L, Scheufele S, Nitschkowski D, Kugler C, Perner S, Reck M, Ammerpohl O, Goldmann T. Marwitz S, et al. Among authors: heinbockel l. Clin Epigenetics. 2017 Nov 28;9:123. doi: 10.1186/s13148-017-0423-6. eCollection 2017. Clin Epigenetics. 2017. PMID: 29209432 Free PMC article.

3

Fountain of youth for squamous cell carcinomas? On the epigenetic age of non-small cell lung cancer and corresponding tumor-free lung tissues.

Marwitz S, Heinbockel L, Scheufele S, Kugler C, Reck M, Rabe KF, Perner S, Goldmann T, Ammerpohl O. Marwitz S, et al. Among authors: heinbockel l. Int J Cancer. 2018 Dec 15;143(12):3061-3070. doi: 10.1002/ijc.31641. Epub 2018 Oct 16. Int J Cancer. 2018. PMID: 29974462 Free PMC article.

4

Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis.

Heinbockel L, Marwitz S, Barcena Varela S, Ferrer-Espada R, Reiling N, Goldmann T, Gutsmann T, Mier W, Schürholz T, Drömann D, Brandenburg K, Martinez de Tejada G. Heinbockel L, et al. PLoS One. 2015 Jul 21;10(7):e0133291. doi: 10.1371/journal.pone.0133291. eCollection 2015. PLoS One. 2015. PMID: 26197109 Free PMC article.

5

Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits.

Bárcena-Varela S, Martínez-de-Tejada G, Martin L, Schuerholz T, Gil-Royo AG, Fukuoka S, Goldmann T, Droemann D, Correa W, Gutsmann T, Brandenburg K, Heinbockel L. Bárcena-Varela S, et al. Among authors: heinbockel l. Exp Mol Med. 2017 Jun 16;49(6):e345. doi: 10.1038/emm.2017.75. Exp Mol Med. 2017. PMID: 28620220 Free PMC article.

6

Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors.

Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Heinbockel L, et al. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7. doi: 10.1128/AAC.02066-12. Epub 2013 Jan 14. Antimicrob Agents Chemother. 2013. PMID: 23318793 Free PMC article.

7

Peptide drug stability: The anti-inflammatory drugs Pep19-2.5 and Pep19-4LF in cream formulation.

Kuhlmann N, Heinbockel L, Correa W, Gutsmann T, Goldmann T, Englisch U, Brandenburg K. Kuhlmann N, et al. Among authors: heinbockel l. Eur J Pharm Sci. 2018 Mar 30;115:240-247. doi: 10.1016/j.ejps.2018.01.022. Epub 2018 Jan 12. Eur J Pharm Sci. 2018. PMID: 29337217

8

LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses.

Pfalzgraff A, Correa W, Heinbockel L, Schromm AB, Lübow C, Gisch N, Martinez-de-Tejada G, Brandenburg K, Weindl G. Pfalzgraff A, et al. Among authors: heinbockel l. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1503-1513. doi: 10.1016/j.bbalip.2019.05.018. Epub 2019 Jun 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31163264

9

Antibacterial action of synthetic antilipopolysaccharide peptides (SALP) involves neutralization of both membrane-bound and free toxins.

Correa W, Heinbockel L, Behrends J, Kaconis Y, Barcena-Varela S, Gutsmann T, Mauss K, Schürholz T, Schromm AB, Martinez de Tejada G, Brandenburg K. Correa W, et al. Among authors: heinbockel l. FEBS J. 2019 Apr;286(8):1576-1593. doi: 10.1111/febs.14805. Epub 2019 Mar 20. FEBS J. 2019. PMID: 30843356 Free article.

10

An update on endotoxin neutralization strategies in Gram-negative bacterial infections.

Brandenburg K, Schromm AB, Weindl G, Heinbockel L, Correa W, Mauss K, Martinez de Tejada G, Garidel P. Brandenburg K, et al. Among authors: heinbockel l. Expert Rev Anti Infect Ther. 2021 Apr;19(4):495-517. doi: 10.1080/14787210.2021.1834847. Epub 2020 Nov 19. Expert Rev Anti Infect Ther. 2021. PMID: 33210958 Review.

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