Janssen A - Search Results

1

Heterochromatin: Guardian of the Genome.

Janssen A, Colmenares SU, Karpen GH. Janssen A, et al. Annu Rev Cell Dev Biol. 2018 Oct 6;34:265-288. doi: 10.1146/annurev-cellbio-100617-062653. Epub 2018 Jul 25. Annu Rev Cell Dev Biol. 2018. PMID: 30044650 Review.

2

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.

Janssen A, Breuer GA, Brinkman EK, van der Meulen AI, Borden SV, van Steensel B, Bindra RS, LaRocque JR, Karpen GH. Janssen A, et al. Genes Dev. 2016 Jul 15;30(14):1645-57. doi: 10.1101/gad.283028.116. Genes Dev. 2016. PMID: 27474442 Free PMC article.

3

Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A.

Janssen A, Colmenares SU, Lee T, Karpen GH. Janssen A, et al. Genes Dev. 2019 Jan 1;33(1-2):103-115. doi: 10.1101/gad.317537.118. Epub 2018 Dec 21. Genes Dev. 2019. PMID: 30578303 Free PMC article.

4

DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5.

Kendek A, Sandron A, Lambooij JP, Colmenares SU, Pociunaite SM, Gooijers I, de Groot L, Karpen GH, Janssen A. Kendek A, et al. Among authors: janssen a. Nucleic Acids Res. 2024 Oct 28;52(19):11753-11767. doi: 10.1093/nar/gkae775. Nucleic Acids Res. 2024. PMID: 39258543 Free PMC article.

5

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair.

Wensveen MR, Dixit AA, van Schendel R, Kendek A, Lambooij JP, Tijsterman M, Colmenares SU, Janssen A. Wensveen MR, et al. Among authors: janssen a. Nat Commun. 2024 Oct 17;15(1):8984. doi: 10.1038/s41467-024-53313-2. Nat Commun. 2024. PMID: 39419979 Free PMC article.

6

Genetic instability: tipping the balance.

Janssen A, Medema RH. Janssen A, et al. Oncogene. 2013 Sep 19;32(38):4459-70. doi: 10.1038/onc.2012.576. Epub 2012 Dec 17. Oncogene. 2013. PMID: 23246960 Review.

7

The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks.

Kendek A, Wensveen MR, Janssen A. Kendek A, et al. Among authors: janssen a. Genes (Basel). 2021 Sep 15;12(9):1415. doi: 10.3390/genes12091415. Genes (Basel). 2021. PMID: 34573397 Free PMC article. Review.

8

Kif15 cooperates with eg5 to promote bipolar spindle assembly.

Tanenbaum ME, Macůrek L, Janssen A, Geers EF, Alvarez-Fernández M, Medema RH. Tanenbaum ME, et al. Among authors: janssen a. Curr Biol. 2009 Nov 3;19(20):1703-11. doi: 10.1016/j.cub.2009.08.027. Epub 2009 Oct 8. Curr Biol. 2009. PMID: 19818618 Free article.

9

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

Janssen A, Kops GJ, Medema RH. Janssen A, et al. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19108-13. doi: 10.1073/pnas.0904343106. Epub 2009 Oct 23. Proc Natl Acad Sci U S A. 2009. PMID: 19855003 Free PMC article.

10

Mitosis as an anti-cancer target.

Janssen A, Medema RH. Janssen A, et al. Oncogene. 2011 Jun 23;30(25):2799-809. doi: 10.1038/onc.2011.30. Epub 2011 Feb 21. Oncogene. 2011. PMID: 21339734 Review.

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