Naldini L - Search Results

1

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens.

Escobar G, Barbarossa L, Barbiera G, Norelli M, Genua M, Ranghetti A, Plati T, Camisa B, Brombin C, Cittaro D, Annoni A, Bondanza A, Ostuni R, Gentner B, Naldini L. Escobar G, et al. Among authors: naldini l. Nat Commun. 2018 Jul 24;9(1):2896. doi: 10.1038/s41467-018-05315-0. Nat Commun. 2018. PMID: 30042420 Free PMC article.

2

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice.

Follenzi A, Battaglia M, Lombardo A, Annoni A, Roncarolo MG, Naldini L. Follenzi A, et al. Among authors: naldini l. Blood. 2004 May 15;103(10):3700-9. doi: 10.1182/blood-2003-09-3217. Epub 2003 Dec 30. Blood. 2004. PMID: 14701690 Free article.

3

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.

Brown BD, Venneri MA, Zingale A, Sergi Sergi L, Naldini L. Brown BD, et al. Among authors: naldini l. Nat Med. 2006 May;12(5):585-91. doi: 10.1038/nm1398. Epub 2006 Apr 23. Nat Med. 2006. PMID: 16633348

4

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration.

Montini E, Cesana D, Schmidt M, Sanvito F, Ponzoni M, Bartholomae C, Sergi Sergi L, Benedicenti F, Ambrosi A, Di Serio C, Doglioni C, von Kalle C, Naldini L. Montini E, et al. Among authors: naldini l. Nat Biotechnol. 2006 Jun;24(6):687-96. doi: 10.1038/nbt1216. Epub 2006 May 28. Nat Biotechnol. 2006. PMID: 16732270

5

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, Brambilla R. Vantaggiato C, et al. Among authors: naldini l. J Biol. 2006;5(5):14. doi: 10.1186/jbiol38. J Biol. 2006. PMID: 16805921 Free PMC article.

6

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

Brown BD, Sitia G, Annoni A, Hauben E, Sergi LS, Zingale A, Roncarolo MG, Guidotti LG, Naldini L. Brown BD, et al. Among authors: naldini l. Blood. 2007 Apr 1;109(7):2797-805. doi: 10.1182/blood-2006-10-049312. Blood. 2007. PMID: 17170119 Free article.

7

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. Annoni A, et al. Among authors: naldini l. Blood. 2007 Sep 15;110(6):1788-96. doi: 10.1182/blood-2006-11-059873. Epub 2007 May 10. Blood. 2007. PMID: 17495135 Free article.

8

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice.

Brown BD, Cantore A, Annoni A, Sergi LS, Lombardo A, Della Valle P, D'Angelo A, Naldini L. Brown BD, et al. Among authors: naldini l. Blood. 2007 Dec 15;110(13):4144-52. doi: 10.1182/blood-2007-03-078493. Epub 2007 Aug 28. Blood. 2007. PMID: 17726165 Free article.

9

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state.

Brown BD, Gentner B, Cantore A, Colleoni S, Amendola M, Zingale A, Baccarini A, Lazzari G, Galli C, Naldini L. Brown BD, et al. Among authors: naldini l. Nat Biotechnol. 2007 Dec;25(12):1457-67. doi: 10.1038/nbt1372. Epub 2007 Nov 16. Nat Biotechnol. 2007. PMID: 18026085

10

Stable knockdown of microRNA in vivo by lentiviral vectors.

Gentner B, Schira G, Giustacchini A, Amendola M, Brown BD, Ponzoni M, Naldini L. Gentner B, et al. Among authors: naldini l. Nat Methods. 2009 Jan;6(1):63-6. doi: 10.1038/nmeth.1277. Epub 2008 Nov 30. Nat Methods. 2009. PMID: 19043411

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