Akbar H - Search Results

1

Small molecule targeting the Rac1-NOX2 interaction prevents collagen-related peptide and thrombin-induced reactive oxygen species generation and platelet activation.

Akbar H, Duan X, Piatt R, Saleem S, Davis AK, Tandon NN, Bergmeier W, Zheng Y. Akbar H, et al. J Thromb Haemost. 2018 Oct;16(10):2083-2096. doi: 10.1111/jth.14240. Epub 2018 Aug 13. J Thromb Haemost. 2018. PMID: 30007118 Free PMC article.

2

Rational design and applications of a Rac GTPase-specific small molecule inhibitor.

Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y. Akbar H, et al. Methods Enzymol. 2006;406:554-65. doi: 10.1016/S0076-6879(06)06043-5. Methods Enzymol. 2006. PMID: 16472687

3

Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation.

Akbar H, Kim J, Funk K, Cancelas JA, Shang X, Chen L, Johnson JF, Williams DA, Zheng Y. Akbar H, et al. J Thromb Haemost. 2007 Aug;5(8):1747-55. doi: 10.1111/j.1538-7836.2007.02646.x. J Thromb Haemost. 2007. PMID: 17663742 Free article.

4

Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.

Akbar H, Shang X, Perveen R, Berryman M, Funk K, Johnson JF, Tandon NN, Zheng Y. Akbar H, et al. PLoS One. 2011;6(7):e22117. doi: 10.1371/journal.pone.0022117. Epub 2011 Jul 18. PLoS One. 2011. PMID: 21789221 Free PMC article.

5

RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets.

Akbar H, Duan X, Saleem S, Davis AK, Zheng Y. Akbar H, et al. PLoS One. 2016 Sep 28;11(9):e0163227. doi: 10.1371/journal.pone.0163227. eCollection 2016. PLoS One. 2016. PMID: 27681226 Free PMC article.

6

Towards increasing shelf life and haemostatic potency of stored platelet concentrates.

Hegde S, Akbar H, Zheng Y, Cancelas JA. Hegde S, et al. Among authors: akbar h. Curr Opin Hematol. 2018 Nov;25(6):500-508. doi: 10.1097/MOH.0000000000000456. Curr Opin Hematol. 2018. PMID: 30281037 Free PMC article. Review.

7

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.

Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, Berryman M, Davis AK, Holinstat M, Zheng Y, Akbar H. Duan X, et al. Among authors: akbar h. Sci Rep. 2021 Jun 23;11(1):13170. doi: 10.1038/s41598-021-92654-6. Sci Rep. 2021. PMID: 34162972 Free PMC article.

8

Rho GTPase Signaling in Platelet Regulation and Implication for Antiplatelet Therapies.

Dandamudi A, Akbar H, Cancelas J, Zheng Y. Dandamudi A, et al. Among authors: akbar h. Int J Mol Sci. 2023 Jan 28;24(3):2519. doi: 10.3390/ijms24032519. Int J Mol Sci. 2023. PMID: 36768837 Free PMC article. Review.

9

Structure-Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents.

Dandamudi A, Seibel W, Tourdot B, Cancelas JA, Akbar H, Zheng Y. Dandamudi A, et al. Among authors: akbar h. Int J Mol Sci. 2023 Feb 19;24(4):4167. doi: 10.3390/ijms24044167. Int J Mol Sci. 2023. PMID: 36835579 Free PMC article.

10

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets.

Hegde S, Akbar H, Wellendorf AM, Nestheide S, Johnson JF, Zhao X, Setchell KD, Zheng Y, Cancelas JA. Hegde S, et al. Among authors: akbar h. Blood. 2024 Oct 17;144(16):1732-1746. doi: 10.1182/blood.2023021453. Blood. 2024. PMID: 39088777

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

189 results

Search Page

Filters