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Senolytics improve physical function and increase lifespan in old age.
Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9.
Nat Med. 2018.
PMID: 29988130
Free PMC article.
Targeting cellular senescence prevents age-related bone loss in mice.
Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S.
Farr JN, et al. Among authors: onken jl.
Nat Med. 2017 Sep;23(9):1072-1079. doi: 10.1038/nm.4385. Epub 2017 Aug 21.
Nat Med. 2017.
PMID: 28825716
Free PMC article.
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Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice.
Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S.
Farr JN, et al. Among authors: onken jl.
Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384c.
Nat Med. 2017.
PMID: 29117174
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miR-219a-5p Regulates Rorβ During Osteoblast Differentiation and in Age-related Bone Loss.
Aquino-Martinez R, Farr JN, Weivoda MM, Negley BA, Onken JL, Thicke BS, Fulcer MM, Fraser DG, van Wijnen AJ, Khosla S, Monroe DG.
Aquino-Martinez R, et al. Among authors: onken jl.
J Bone Miner Res. 2019 Jan;34(1):135-144. doi: 10.1002/jbmr.3586. Epub 2018 Oct 15.
J Bone Miner Res. 2019.
PMID: 30321475
Free PMC article.
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Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice.
Farr JN, Weivoda MM, Nicks KM, Fraser DG, Negley BA, Onken JL, Thicke BS, Ruan M, Liu H, Forrest D, Hawse JR, Khosla S, Monroe DG.
Farr JN, et al. Among authors: onken jl.
J Bone Miner Res. 2018 Apr;33(4):720-731. doi: 10.1002/jbmr.3351. Epub 2017 Dec 27.
J Bone Miner Res. 2018.
PMID: 29206307
Free PMC article.
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All-Trans-Retinoic Acid Enhances Mitochondrial Function in Models of Human Liver.
Tripathy S, Chapman JD, Han CY, Hogarth CA, Arnold SL, Onken J, Kent T, Goodlett DR, Isoherranen N.
Tripathy S, et al.
Mol Pharmacol. 2016 May;89(5):560-74. doi: 10.1124/mol.116.103697. Epub 2016 Feb 26.
Mol Pharmacol. 2016.
Retraction in:
Mol Pharmacol. 2020 Feb;97(2):61. doi: 10.1124/mol.116.103697retraction.
PMID: 26921399
Free PMC article.
Retracted.
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CYP26 Enzymes Are Necessary Within the Postnatal Seminiferous Epithelium for Normal Murine Spermatogenesis.
Hogarth CA, Evans E, Onken J, Kent T, Mitchell D, Petkovich M, Griswold MD.
Hogarth CA, et al.
Biol Reprod. 2015 Jul;93(1):19. doi: 10.1095/biolreprod.115.129718. Epub 2015 Jun 3.
Biol Reprod. 2015.
PMID: 26040672
Free PMC article.
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Characterizing the Spermatogonial Response to Retinoic Acid During the Onset of Spermatogenesis and Following Synchronization in the Neonatal Mouse Testis.
Agrimson KS, Onken J, Mitchell D, Topping TB, Chiarini-Garcia H, Hogarth CA, Griswold MD.
Agrimson KS, et al.
Biol Reprod. 2016 Oct;95(4):81. doi: 10.1095/biolreprod.116.141770. Epub 2016 Aug 3.
Biol Reprod. 2016.
PMID: 27488029
Free PMC article.
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