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Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.
Jones MG, Andriotis OG, Roberts JJ, Lunn K, Tear VJ, Cao L, Ask K, Smart DE, Bonfanti A, Johnson P, Alzetani A, Conforti F, Doherty R, Lai CY, Johnson B, Bourdakos KN, Fletcher SV, Marshall BG, Jogai S, Brereton CJ, Chee SJ, Ottensmeier CH, Sime P, Gauldie J, Kolb M, Mahajan S, Fabre A, Bhaskar A, Jarolimek W, Richeldi L, O'Reilly KM, Monk PD, Thurner PJ, Davies DE. Jones MG, et al. Among authors: bhaskar a. Elife. 2018 Jul 3;7:e36354. doi: 10.7554/eLife.36354. Elife. 2018. PMID: 29966587 Free PMC article.
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis.
Brereton CJ, Yao L, Davies ER, Zhou Y, Vukmirovic M, Bell JA, Wang S, Ridley RA, Dean LSN, Andriotis OG, Conforti F, Brewitz L, Mohammed S, Wallis T, Tavassoli A, Ewing RM, Alzetani A, Marshall BG, Fletcher SV, Thurner PJ, Fabre A, Kaminski N, Richeldi L, Bhaskar A, Schofield CJ, Loxham M, Davies DE, Wang Y, Jones MG. Brereton CJ, et al. Among authors: bhaskar a. Elife. 2022 Feb 21;11:e69348. doi: 10.7554/eLife.69348. Elife. 2022. PMID: 35188460 Free PMC article.
Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE.
Lynn SA, Ward G, Keeling E, Scott JA, Cree AJ, Johnston DA, Page A, Cuan-Urquizo E, Bhaskar A, Grossel MC, Tumbarello DA, Newman TA, Lotery AJ, Ratnayaka JA. Lynn SA, et al. Among authors: bhaskar a. Tissue Cell. 2017 Aug;49(4):447-460. doi: 10.1016/j.tice.2017.06.003. Epub 2017 Jun 19. Tissue Cell. 2017. PMID: 28669519 Free PMC article.
Revitalizing antimicrobial strategies: paromomycin and dicoumarol repurposed as potent inhibitors of M.tb's replication machinery via targeting the vital protein DnaN.
Ali W, Agarwal M, Jamal S, Gangwar R, Sharma R, Mubarak MM, Wani ZA, Ahmad Z, Khan A, Sheikh JA, Grover A, Bhaskar A, Dwivedi VP, Grover S. Ali W, et al. Among authors: bhaskar a. Int J Biol Macromol. 2024 Oct;278(Pt 3):134652. doi: 10.1016/j.ijbiomac.2024.134652. Epub 2024 Aug 22. Int J Biol Macromol. 2024. PMID: 39173789
292 results