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Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.
Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q, Vanderhoydonck B, Gao LJ, Jang MY, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan AR, Henshall J, Jairaj M, Malcolm S, Ward E, Shuttleworth L, Lin Y, Li S, Louat T, Waer M, Herman J, Payne A, Ceska T, Doyle C, Pitt W, Calmiano M, Augustin M, Steinbacher S, Lammens A, Allen R. Reuberson J, et al. Among authors: ward e. J Med Chem. 2018 Aug 9;61(15):6705-6723. doi: 10.1021/acs.jmedchem.8b00521. Epub 2018 Jul 19. J Med Chem. 2018. PMID: 29952567
Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Rowley TF, Peters SJ, Aylott M, Griffin R, Davies NL, Healy LJ, Cutler RM, Eddleston A, Pither TL, Sopp JM, Zaccheo O, Fossati G, Cain K, Ventom AM, Hailu H, Ward EJ, Sherington J, Brennan FR, Fallah-Arani F, Humphreys DP. Rowley TF, et al. Commun Biol. 2018 Sep 14;1:146. doi: 10.1038/s42003-018-0149-9. eCollection 2018. Commun Biol. 2018. PMID: 30272022 Free PMC article.
Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.
Qureshi OS, Rowley TF, Junker F, Peters SJ, Crilly S, Compson J, Eddleston A, Björkelund H, Greenslade K, Parkinson M, Davies NL, Griffin R, Pither TL, Cain K, Christodoulou L, Staelens L, Ward E, Tibbitts J, Kiessling A, Smith B, Brennan FR, Malmqvist M, Fallah-Arani F, Humphreys DP. Qureshi OS, et al. Among authors: ward e. Sci Rep. 2017 Dec 6;7(1):17049. doi: 10.1038/s41598-017-17255-8. Sci Rep. 2017. PMID: 29213127 Free PMC article.
The Context of the Emergency Department as a Location for a Smoking Cessation Intervention-Process Evaluation Findings From the Cessation of Smoking Trial in the Emergency Department Trial.
Notley C, Belderson P, Ward E, Clark LV, Clark A, Stirling S, Parrott S, Li J, Coats TJ, Bauld L, Holland R, Gentry S, Agrawal S, Bloom BM, Boyle A, Gray A, Morris MG, Pope I. Notley C, et al. Among authors: ward e. Nicotine Tob Res. 2024 Nov 7:ntae223. doi: 10.1093/ntr/ntae223. Online ahead of print. Nicotine Tob Res. 2024. PMID: 39505370
Cost-utility analysis of provision of e-cigarette starter kits for smoking cessation in emergency departments: An economic evaluation of a randomized controlled trial.
Li J, Wu Q, Parrott S, Pope I, Clark LV, Clark A, Ward E, Belderson P, Stirling S, Coats TJ, Bauld L, Holland R, Gentry S, Agrawal S, Bloom BM, Boyle A, Gray A, Morris MG, Livingstone-Banks J, Notley C. Li J, et al. Among authors: ward e. Addiction. 2024 Oct 31. doi: 10.1111/add.16698. Online ahead of print. Addiction. 2024. PMID: 39482840
1,733 results