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Page 1
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.
Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, Vanderhoydonc F, Duarte JAG, Bosisio F, Van den Eynde K, Nys K, Pérez MV, Agostinis P, Waelkens E, Van den Oord J, Fendt SM, Marine JC, Swinnen JV. Talebi A, et al. Among authors: fendt sm. Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0. Nat Commun. 2018. PMID: 29950559 Free PMC article.
Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Schoors S, Bruning U, Missiaen R, Queiroz KC, Borgers G, Elia I, Zecchin A, Cantelmo AR, Christen S, Goveia J, Heggermont W, Goddé L, Vinckier S, Van Veldhoven PP, Eelen G, Schoonjans L, Gerhardt H, Dewerchin M, Baes M, De Bock K, Ghesquière B, Lunt SY, Fendt SM, Carmeliet P. Schoors S, et al. Among authors: fendt sm. Nature. 2015 Apr 9;520(7546):192-197. doi: 10.1038/nature14362. Epub 2015 Apr 1. Nature. 2015. PMID: 25830893 Free PMC article.
The role of fatty acid β-oxidation in lymphangiogenesis.
Wong BW, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, García-Caballero M, Missiaen R, Huang H, Brüning U, Blacher S, Vinckier S, Goveia J, Knobloch M, Zhao H, Dierkes C, Shi C, Hägerling R, Moral-Dardé V, Wyns S, Lippens M, Jessberger S, Fendt SM, Luttun A, Noel A, Kiefer F, Ghesquière B, Moons L, Schoonjans L, Dewerchin M, Eelen G, Lambrechts D, Carmeliet P. Wong BW, et al. Among authors: fendt sm. Nature. 2017 Feb 2;542(7639):49-54. doi: 10.1038/nature21028. Epub 2016 Dec 26. Nature. 2017. PMID: 28024299
Inhibition of glutamine synthetase in monocytes from patients with acute-on-chronic liver failure resuscitates their antibacterial and inflammatory capacity.
Korf H, du Plessis J, van Pelt J, De Groote S, Cassiman D, Verbeke L, Ghesquière B, Fendt SM, Bird MJ, Talebi A, Van Haele M, Feio-Azevedo R, Meelberghs L, Roskams T, Mookerjee RP, Mehta G, Jalan R, Gustot T, Laleman W, Nevens F, van der Merwe SW. Korf H, et al. Among authors: fendt sm. Gut. 2019 Oct;68(10):1872-1883. doi: 10.1136/gutjnl-2018-316888. Epub 2018 Dec 22. Gut. 2019. PMID: 30580251
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM. Vriens K, et al. Among authors: fendt sm. Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6. Nature. 2019. PMID: 30728499 Free PMC article.
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM. Elia I, et al. Among authors: fendt sm. Nature. 2019 Apr;568(7750):117-121. doi: 10.1038/s41586-019-0977-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814728 Free PMC article.
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt SM, De Keersmaecker K. Kampen KR, et al. Among authors: fendt sm. Nat Commun. 2019 Jun 11;10(1):2542. doi: 10.1038/s41467-019-10508-2. Nat Commun. 2019. PMID: 31186416 Free PMC article.
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism.
Vandoorne T, Veys K, Guo W, Sicart A, Vints K, Swijsen A, Moisse M, Eelen G, Gounko NV, Fumagalli L, Fazal R, Germeys C, Quaegebeur A, Fendt SM, Carmeliet P, Verfaillie C, Van Damme P, Ghesquière B, De Bock K, Van Den Bosch L. Vandoorne T, et al. Among authors: fendt sm. Nat Commun. 2019 Sep 12;10(1):4147. doi: 10.1038/s41467-019-12099-4. Nat Commun. 2019. PMID: 31515480 Free PMC article.
Analyzing the Metabolism of Metastases in Mice.
Altea-Manzano P, Broekaert D, Duarte JAG, Fernández-García J, Planque M, Fendt SM. Altea-Manzano P, et al. Among authors: fendt sm. Methods Mol Biol. 2020;2088:93-118. doi: 10.1007/978-1-0716-0159-4_6. Methods Mol Biol. 2020. PMID: 31893372
122 results