Agostinis P - Search Results

1

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.

Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, Vanderhoydonc F, Duarte JAG, Bosisio F, Van den Eynde K, Nys K, Pérez MV, Agostinis P, Waelkens E, Van den Oord J, Fendt SM, Marine JC, Swinnen JV. Talebi A, et al. Among authors: agostinis p. Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0. Nat Commun. 2018. PMID: 29950559 Free PMC article.

2

Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes.

Van Laethem A, Nys K, Van Kelst S, Claerhout S, Ichijo H, Vandenheede JR, Garmyn M, Agostinis P. Van Laethem A, et al. Among authors: agostinis p. Free Radic Biol Med. 2006 Nov 1;41(9):1361-71. doi: 10.1016/j.freeradbiomed.2006.07.007. Epub 2006 Jul 15. Free Radic Biol Med. 2006. PMID: 17023263

3

A p38(MAPK)/HIF-1 pathway initiated by UVB irradiation is required to induce Noxa and apoptosis of human keratinocytes.

Nys K, Van Laethem A, Michiels C, Rubio N, Piette JG, Garmyn M, Agostinis P. Nys K, et al. Among authors: agostinis p. J Invest Dermatol. 2010 Sep;130(9):2269-76. doi: 10.1038/jid.2010.93. Epub 2010 Apr 15. J Invest Dermatol. 2010. PMID: 20393480 Free article.

4

Uncovering the role of hypoxia inducible factor-1α in skin carcinogenesis.

Nys K, Maes H, Dudek AM, Agostinis P. Nys K, et al. Among authors: agostinis p. Biochim Biophys Acta. 2011 Aug;1816(1):1-12. doi: 10.1016/j.bbcan.2011.02.001. Epub 2011 Feb 19. Biochim Biophys Acta. 2011. PMID: 21338656 Review.

5

Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim.

Nys K, Maes H, Andrei G, Snoeck R, Garmyn M, Agostinis P. Nys K, et al. Among authors: agostinis p. Free Radic Biol Med. 2012 Mar 15;52(6):1111-20. doi: 10.1016/j.freeradbiomed.2011.12.017. Epub 2012 Jan 2. Free Radic Biol Med. 2012. PMID: 22245094

6

Bcl-2 family members: essential players in skin cancer.

Nys K, Agostinis P. Nys K, et al. Among authors: agostinis p. Cancer Lett. 2012 Jul 1;320(1):1-13. doi: 10.1016/j.canlet.2012.01.031. Epub 2012 Jan 25. Cancer Lett. 2012. PMID: 22281242 Review.

7

Autophagy: a new target or an old strategy for the treatment of Crohn's disease?

Nys K, Agostinis P, Vermeire S. Nys K, et al. Among authors: agostinis p. Nat Rev Gastroenterol Hepatol. 2013 Jul;10(7):395-401. doi: 10.1038/nrgastro.2013.66. Epub 2013 Apr 16. Nat Rev Gastroenterol Hepatol. 2013. PMID: 23591407 Review.

8

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim.

Verfaillie T, van Vliet A, Garg AD, Dewaele M, Rubio N, Gupta S, de Witte P, Samali A, Agostinis P. Verfaillie T, et al. Among authors: agostinis p. Biochem Biophys Res Commun. 2013 Aug 30;438(3):500-6. doi: 10.1016/j.bbrc.2013.07.107. Epub 2013 Aug 2. Biochem Biophys Res Commun. 2013. PMID: 23916707

9

The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.

Wouters J, Stas M, Gremeaux L, Govaere O, Van den Broeck A, Maes H, Agostinis P, Roskams T, van den Oord JJ, Vankelecom H. Wouters J, et al. Among authors: agostinis p. PLoS One. 2013 Oct 3;8(10):e76550. doi: 10.1371/journal.pone.0076550. eCollection 2013. PLoS One. 2013. PMID: 24098529 Free PMC article.

10

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

Hoefkens E, Nys K, John JM, Van Steen K, Arijs I, Van der Goten J, Van Assche G, Agostinis P, Rutgeerts P, Vermeire S, Cleynen I. Hoefkens E, et al. Among authors: agostinis p. Autophagy. 2013 Dec;9(12):2046-55. doi: 10.4161/auto.26337. Epub 2013 Nov 14. Autophagy. 2013. PMID: 24247223

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