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Page 1
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
Gusarova V, O'Dushlaine C, Teslovich TM, Benotti PN, Mirshahi T, Gottesman O, Van Hout CV, Murray MF, Mahajan A, Nielsen JB, Fritsche L, Wulff AB, Gudbjartsson DF, Sjögren M, Emdin CA, Scott RA, Lee WJ, Small A, Kwee LC, Dwivedi OP, Prasad RB, Bruse S, Lopez AE, Penn J, Marcketta A, Leader JB, Still CD, Kirchner HL, Mirshahi UL, Wardeh AH, Hartle CM, Habegger L, Fetterolf SN, Tusie-Luna T, Morris AP, Holm H, Steinthorsdottir V, Sulem P, Thorsteinsdottir U, Rotter JI, Chuang LM, Damrauer S, Birtwell D, Brummett CM, Khera AV, Natarajan P, Orho-Melander M, Flannick J, Lotta LA, Willer CJ, Holmen OL, Ritchie MD, Ledbetter DH, Murphy AJ, Borecki IB, Reid JG, Overton JD, Hansson O, Groop L, Shah SH, Kraus WE, Rader DJ, Chen YI, Hveem K, Wareham NJ, Kathiresan S, Melander O, Stefansson K, Nordestgaard BG, Tybjærg-Hansen A, Abecasis GR, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Yancopoulos GD, Carey DJ, Shuldiner AR, Baras A, Dewey FE, Gromada J. Gusarova V, et al. Among authors: kwee lc. Nat Commun. 2018 Jun 13;9(1):2252. doi: 10.1038/s41467-018-04611-z. Nat Commun. 2018. PMID: 29899519 Free PMC article.
Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis.
Kraus WE, Muoio DM, Stevens R, Craig D, Bain JR, Grass E, Haynes C, Kwee L, Qin X, Slentz DH, Krupp D, Muehlbauer M, Hauser ER, Gregory SG, Newgard CB, Shah SH. Kraus WE, et al. PLoS Genet. 2015 Nov 5;11(11):e1005553. doi: 10.1371/journal.pgen.1005553. eCollection 2015 Nov. PLoS Genet. 2015. PMID: 26540294 Free PMC article.
Evaluating DNA methylation age on the Illumina MethylationEPIC Bead Chip.
Dhingra R, Kwee LC, Diaz-Sanchez D, Devlin RB, Cascio W, Hauser ER, Gregory S, Shah S, Kraus WE, Olden K, Ward-Caviness CK. Dhingra R, et al. Among authors: kwee lc. PLoS One. 2019 Apr 19;14(4):e0207834. doi: 10.1371/journal.pone.0207834. eCollection 2019. PLoS One. 2019. PMID: 31002714 Free PMC article.
Identification of Undetected Monogenic Cardiovascular Disorders.
Abdulrahim JW, Kwee LC, Alenezi F, Sun AY, Baras A, Ajayi TA, Henao R, Holley CL, McGarrah RW, Daubert JP, Truby LK, Vemulapalli S, Wang A, Khouri MG, Shah SH. Abdulrahim JW, et al. Among authors: kwee lc. J Am Coll Cardiol. 2020 Aug 18;76(7):797-808. doi: 10.1016/j.jacc.2020.06.037. J Am Coll Cardiol. 2020. PMID: 32792077 Free PMC article.
Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution.
Ward-Caviness CK, Russell AG, Weaver AM, Slawsky E, Dhingra R, Kwee LC, Jiang R, Neas LM, Diaz-Sanchez D, Devlin RB, Cascio WE, Olden K, Hauser ER, Shah SH, Kraus WE. Ward-Caviness CK, et al. Among authors: kwee lc. Aging (Albany NY). 2020 Dec 7;12(23):24141-24155. doi: 10.18632/aging.202341. Epub 2020 Dec 7. Aging (Albany NY). 2020. PMID: 33289704 Free PMC article.
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus.
van Zuydam NR, Ladenvall C, Voight BF, Strawbridge RJ, Fernandez-Tajes J, Rayner NW, Robertson NR, Mahajan A, Vlachopoulou E, Goel A, Kleber ME, Nelson CP, Kwee LC, Esko T, Mihailov E, Mägi R, Milani L, Fischer K, Kanoni S, Kumar J, Song C, Hartiala JA, Pedersen NL, Perola M, Gieger C, Peters A, Qu L, Willems SM, Doney ASF, Morris AD, Zheng Y, Sesti G, Hu FB, Qi L, Laakso M, Thorsteinsdottir U, Grallert H, van Duijn C, Reilly MP, Ingelsson E, Deloukas P, Kathiresan S, Metspalu A, Shah SH, Sinisalo J, Salomaa V, Hamsten A, Samani NJ, März W, Hazen SL, Watkins H, Saleheen D, Morris AP, Colhoun HM, Groop L, McCarthy MI, Palmer CNA; SUMMIT Steering Committee; CARDIOGRAMplusC4D Steering Committee*. van Zuydam NR, et al. Among authors: kwee lc. Circ Genom Precis Med. 2020 Dec;13(6):e002769. doi: 10.1161/CIRCGEN.119.002769. Epub 2020 Aug 13. Circ Genom Precis Med. 2020. PMID: 33321069 Free PMC article.
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