Gleitz HF - Search Results

1

Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms.

Gleitz HF, Liao AY, Cook JR, Rowlston SF, Forte GM, D'Souza Z, O'Leary C, Holley RJ, Bigger BW. Gleitz HF, et al. EMBO Mol Med. 2018 Jul;10(7):e8730. doi: 10.15252/emmm.201708730. EMBO Mol Med. 2018. PMID: 29884617 Free PMC article.

2

Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II.

Gleitz HF, O'Leary C, Holley RJ, Bigger BW. Gleitz HF, et al. PLoS One. 2017 Feb 16;12(2):e0172435. doi: 10.1371/journal.pone.0172435. eCollection 2017. PLoS One. 2017. PMID: 28207863 Free PMC article.

3

Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.

Holley RJ, Ellison SM, Fil D, O'Leary C, McDermott J, Senthivel N, Langford-Smith AWW, Wilkinson FL, D'Souza Z, Parker H, Liao A, Rowlston S, Gleitz HFE, Kan SH, Dickson PI, Bigger BW. Holley RJ, et al. Brain. 2018 Jan 1;141(1):99-116. doi: 10.1093/brain/awx311. Brain. 2018. PMID: 29186350

4

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, Dridi L, Martins C, Levade T, Stacey KB, Davis DM, Dyer A, Clément N, Björklund T, Ali RR, Agbandje-McKenna M, Rahim AA, Pshezhetsky A, Waddington SN, Linden RM, Bigger BW, Henckaerts E. Tordo J, et al. Brain. 2018 Jul 1;141(7):2014-2031. doi: 10.1093/brain/awy126. Brain. 2018. PMID: 29788236 Free PMC article.

5

An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA.

Gray AL, O'Leary C, Liao A, Agúndez L, Youshani AS, Gleitz HF, Parker H, Taylor JT, Danos O, Hocquemiller M, Palomar N, Linden RM, Henckaerts E, Holley RJ, Bigger BW. Gray AL, et al. Among authors: gleitz hf. Hum Gene Ther. 2019 Sep;30(9):1052-1066. doi: 10.1089/hum.2018.189. Epub 2019 Jun 4. Hum Gene Ther. 2019. PMID: 31020862

6

Fusion of Rabies Virus Glycoprotein or gh625 to Iduronate-2-Sulfatase for the Treatment of Mucopolysaccharidosis Type II.

Wood SR, Chaudrhy A, Ellison S, Searle R, Burgod C, Tehseen G, Forte G, O'Leary C, Gleitz H, Liao A, Cook J, Holley R, Bigger BW. Wood SR, et al. Hum Gene Ther. 2024 Apr;35(7-8):232-242. doi: 10.1089/hum.2023.025. Epub 2023 Jul 7. Hum Gene Ther. 2024. PMID: 37212263

7

Sustained long-term disease correction in a murine model of MPSII following stem cell gene therapy.

Ellison S, Liao A, Gleitz HFE, Parker H, Booth L, Robinson J, Wood S, Taylor J, Holley R, Bigger BW. Ellison S, et al. Among authors: gleitz hfe. Mol Ther Methods Clin Dev. 2023 Oct 20;31:101127. doi: 10.1016/j.omtm.2023.101127. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37920237 Free PMC article.

8

Still a burning question: the interplay between inflammation and fibrosis in myeloproliferative neoplasms.

Gleitz HFE, Benabid A, Schneider RK. Gleitz HFE, et al. Curr Opin Hematol. 2021 Sep 1;28(5):364-371. doi: 10.1097/MOH.0000000000000669. Curr Opin Hematol. 2021. PMID: 34232140 Free PMC article. Review.

9

Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis.

Gleitz HF, Kramann R, Schneider RK. Gleitz HF, et al. J Pathol. 2018 Jun;245(2):138-146. doi: 10.1002/path.5078. Epub 2018 Apr 19. J Pathol. 2018. PMID: 29570794 Free PMC article. Review.

10

Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing.

Gleitz HFE, Snoeren IAM, Fuchs SNR, Leimkühler NB, Schneider RK. Gleitz HFE, et al. STAR Protoc. 2021 May 12;2(2):100538. doi: 10.1016/j.xpro.2021.100538. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34027494 Free PMC article.

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