Taylor AE - Search Results

1

Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.

Chortis V, Taylor AE, Doig CL, Walsh MD, Meimaridou E, Jenkinson C, Rodriguez-Blanco G, Ronchi CL, Jafri A, Metherell LA, Hebenstreit D, Dunn WB, Arlt W, Foster PA. Chortis V, et al. Among authors: taylor ae. Endocrinology. 2018 Aug 1;159(8):2836-2849. doi: 10.1210/en.2018-00014. Endocrinology. 2018. PMID: 29850793 Free PMC article.

2

Dehydroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation.

Radford DJ, Wang K, McNelis JC, Taylor AE, Hechenberger G, Hofmann J, Chahal H, Arlt W, Lord JM. Radford DJ, et al. Among authors: taylor ae. Mol Endocrinol. 2010 Apr;24(4):813-21. doi: 10.1210/me.2009-0390. Epub 2010 Feb 19. Mol Endocrinol. 2010. PMID: 20172962 Free PMC article.

3

A novel entity of clinically isolated adrenal insufficiency caused by a partially inactivating mutation of the gene encoding for P450 side chain cleavage enzyme (CYP11A1).

Parajes S, Kamrath C, Rose IT, Taylor AE, Mooij CF, Dhir V, Grötzinger J, Arlt W, Krone N. Parajes S, et al. Among authors: taylor ae. J Clin Endocrinol Metab. 2011 Nov;96(11):E1798-806. doi: 10.1210/jc.2011-1277. Epub 2011 Aug 31. J Clin Endocrinol Metab. 2011. PMID: 21880796

4

Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors.

Arlt W, Biehl M, Taylor AE, Hahner S, Libé R, Hughes BA, Schneider P, Smith DJ, Stiekema H, Krone N, Porfiri E, Opocher G, Bertherat J, Mantero F, Allolio B, Terzolo M, Nightingale P, Shackleton CH, Bertagna X, Fassnacht M, Stewart PM. Arlt W, et al. Among authors: taylor ae. J Clin Endocrinol Metab. 2011 Dec;96(12):3775-84. doi: 10.1210/jc.2011-1565. Epub 2011 Sep 14. J Clin Endocrinol Metab. 2011. PMID: 21917861 Free PMC article.

5

Delayed diagnosis of adrenal insufficiency in a patient with severe penoscrotal hypospadias due to two novel P450 side-change cleavage enzyme (CYP11A1) mutations (p.R360W; p.R405X).

Parajes S, Chan AO, But WM, Rose IT, Taylor AE, Dhir V, Arlt W, Krone N. Parajes S, et al. Among authors: taylor ae. Eur J Endocrinol. 2012 Dec;167(6):881-5. doi: 10.1530/EJE-12-0450. Epub 2012 Sep 11. Eur J Endocrinol. 2012. PMID: 22968487 Free PMC article.

6

Fluconazole inhibits human adrenocortical steroidogenesis in vitro.

van der Pas R, Hofland LJ, Hofland J, Taylor AE, Arlt W, Steenbergen J, van Koetsveld PM, de Herder WW, de Jong FH, Feelders RA. van der Pas R, et al. Among authors: taylor ae. J Endocrinol. 2012 Dec;215(3):403-12. doi: 10.1530/JOE-12-0310. Epub 2012 Oct 4. J Endocrinol. 2012. PMID: 23038793

7

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio.

Haring R, Wallaschofski H, Teumer A, Kroemer H, Taylor AE, Shackleton CH, Nauck M, Völker U, Homuth G, Arlt W. Haring R, et al. Among authors: taylor ae. J Mol Endocrinol. 2012 Dec 31;50(1):73-7. doi: 10.1530/JME-12-0185. Print 2013 Feb. J Mol Endocrinol. 2012. PMID: 23132913 Free PMC article.

8

Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.

Chortis V, Taylor AE, Schneider P, Tomlinson JW, Hughes BA, O'Neil DM, Libé R, Allolio B, Bertagna X, Bertherat J, Beuschlein F, Fassnacht M, Karavitaki N, Mannelli M, Mantero F, Opocher G, Porfiri E, Quinkler M, Sherlock M, Terzolo M, Nightingale P, Shackleton CH, Stewart PM, Hahner S, Arlt W. Chortis V, et al. Among authors: taylor ae. J Clin Endocrinol Metab. 2013 Jan;98(1):161-71. doi: 10.1210/jc.2012-2851. Epub 2012 Nov 16. J Clin Endocrinol Metab. 2013. PMID: 23162091 Free article. Clinical Trial.

9

Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme cyp11a2.

Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, Arlt W, Shackleton C, Müller F, Krone N. Parajes S, et al. Among authors: taylor ae. Endocrinology. 2013 Aug;154(8):2702-11. doi: 10.1210/en.2013-1145. Epub 2013 May 13. Endocrinology. 2013. PMID: 23671259

10

Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione.

O'Reilly MW, Taylor AE, Crabtree NJ, Hughes BA, Capper F, Crowley RK, Stewart PM, Tomlinson JW, Arlt W. O'Reilly MW, et al. Among authors: taylor ae. J Clin Endocrinol Metab. 2014 Mar;99(3):1027-36. doi: 10.1210/jc.2013-3399. Epub 2014 Jan 1. J Clin Endocrinol Metab. 2014. PMID: 24423344 Free PMC article.

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