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Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.
Ng SY, Yoshida N, Christie AL, Ghandi M, Dharia NV, Dempster J, Murakami M, Shigemori K, Morrow SN, Van Scoyk A, Cordero NA, Stevenson KE, Puligandla M, Haas B, Lo C, Meyers R, Gao G, Cherniack A, Louissaint A Jr, Nardi V, Thorner AR, Long H, Qiu X, Morgan EA, Dorfman DM, Fiore D, Jang J, Epstein AL, Dogan A, Zhang Y, Horwitz SM, Jacobsen ED, Santiago S, Ren JG, Guerlavais V, Annis DA, Aivado M, Saleh MN, Mehta A, Tsherniak A, Root D, Vazquez F, Hahn WC, Inghirami G, Aster JC, Weinstock DM, Koch R. Ng SY, et al. Among authors: fiore d. Nat Commun. 2018 May 22;9(1):2024. doi: 10.1038/s41467-018-04356-9. Nat Commun. 2018. PMID: 29789628 Free PMC article.
Peripheral T cell lymphomas: from the bench to the clinic.
Fiore D, Cappelli LV, Broccoli A, Zinzani PL, Chan WC, Inghirami G. Fiore D, et al. Nat Rev Cancer. 2020 Jun;20(6):323-342. doi: 10.1038/s41568-020-0247-0. Epub 2020 Apr 6. Nat Rev Cancer. 2020. PMID: 32249838 Review.
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen Y, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K. Garcia-Bermudez J, et al. Among authors: fiore d. Nature. 2019 Mar;567(7746):118-122. doi: 10.1038/s41586-019-0945-5. Epub 2019 Feb 13. Nature. 2019. PMID: 30760928 Free PMC article.
A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries.
Fiore D, Cappelli LV, Zumbo P, Phillips JM, Liu Z, Cheng S, Yoffe L, Ghione P, Di Maggio F, Dogan A, Khodos I, de Stanchina E, Casano J, Kayembe C, Tam W, Betel D, Foa' R, Cerchietti L, Rabadan R, Horwitz S, Weinstock DM, Inghirami G. Fiore D, et al. Cancers (Basel). 2020 Jun 17;12(6):1603. doi: 10.3390/cancers12061603. Cancers (Basel). 2020. PMID: 32560455 Free PMC article.
Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities.
Cappelli LV, Fiore D, Phillip JM, Yoffe L, Di Giacomo F, Chiu W, Hu Y, Kayembe C, Ginsberg M, Consolino L, Barcia Duran JG, Zamponi N, Melnick AM, Boccalatte F, Tam W, Elemento O, Chiaretti S, Guarini A, Foà R, Cerchietti L, Rafii S, Inghirami G. Cappelli LV, et al. Among authors: fiore d. Blood. 2023 Feb 2;141(5):503-518. doi: 10.1182/blood.2022015414. Blood. 2023. PMID: 35981563 Free PMC article.
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.
Abate F, da Silva-Almeida AC, Zairis S, Robles-Valero J, Couronne L, Khiabanian H, Quinn SA, Kim MY, Laginestra MA, Kim C, Fiore D, Bhagat G, Piris MA, Campo E, Lossos IS, Bernard OA, Inghirami G, Pileri S, Bustelo XR, Rabadan R, Ferrando AA, Palomero T. Abate F, et al. Among authors: fiore d. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):764-769. doi: 10.1073/pnas.1608839114. Epub 2017 Jan 6. Proc Natl Acad Sci U S A. 2017. PMID: 28062691 Free PMC article.
The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.
Fragliasso V, Verma A, Manzotti G, Tameni A, Bareja R, Heavican TB, Iqbal J, Wang R, Fiore D, Mularoni V, Chan WC, Lhoumaud P, Skok J, Zanetti E, Merli F, Ciarrocchi A, Elemento O, Inghirami G. Fragliasso V, et al. Among authors: fiore d. Leukemia. 2020 Nov;34(11):2964-2980. doi: 10.1038/s41375-020-0754-8. Epub 2020 Mar 2. Leukemia. 2020. PMID: 32123306
Aptamer-miR-34c Conjugate Affects Cell Proliferation of Non-Small-Cell Lung Cancer Cells.
Russo V, Paciocco A, Affinito A, Roscigno G, Fiore D, Palma F, Galasso M, Volinia S, Fiorelli A, Esposito CL, Nuzzo S, Inghirami G, de Franciscis V, Condorelli G. Russo V, et al. Among authors: fiore d. Mol Ther Nucleic Acids. 2018 Dec 7;13:334-346. doi: 10.1016/j.omtn.2018.09.016. Epub 2018 Sep 27. Mol Ther Nucleic Acids. 2018. PMID: 30340138 Free PMC article.
Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL.
Iaboni M, Russo V, Fontanella R, Roscigno G, Fiore D, Donnarumma E, Esposito CL, Quintavalle C, Giangrande PH, de Franciscis V, Condorelli G. Iaboni M, et al. Among authors: fiore d. Mol Ther Nucleic Acids. 2016 Mar 8;5(3):e289. doi: 10.1038/mtna.2016.5. Mol Ther Nucleic Acids. 2016. PMID: 27111415 Free PMC article.
295 results