Niwa S - Search Results

1

A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability.

Chia PH, Zhong FL, Niwa S, Bonnard C, Utami KH, Zeng R, Lee H, Eskin A, Nelson SF, Xie WH, Al-Tawalbeh S, El-Khateeb M, Shboul M, Pouladi MA, Al-Raqad M, Reversade B. Chia PH, et al. Among authors: niwa s. Elife. 2018 May 22;7:e32451. doi: 10.7554/eLife.32451. Elife. 2018. PMID: 29784083 Free PMC article.

2

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation.

Imasaki T, Kikkawa S, Niwa S, Saijo-Hamano Y, Shigematsu H, Aoyama K, Mitsuoka K, Shimizu T, Aoki M, Sakamoto A, Tomabechi Y, Sakai N, Shirouzu M, Taguchi S, Yamagishi Y, Setsu T, Sakihama Y, Nitta E, Takeichi M, Nitta R. Imasaki T, et al. Among authors: niwa s. Elife. 2022 Jun 28;11:e77365. doi: 10.7554/eLife.77365. Elife. 2022. PMID: 35762204 Free PMC article.

3

Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex.

Taguchi S, Nakano J, Imasaki T, Kita T, Saijo-Hamano Y, Sakai N, Shigematsu H, Okuma H, Shimizu T, Nitta E, Kikkawa S, Mizobuchi S, Niwa S, Nitta R. Taguchi S, et al. Among authors: niwa s. Elife. 2022 Sep 6;11:e77877. doi: 10.7554/eLife.77877. Elife. 2022. PMID: 36065637 Free PMC article.

4

Comparative analysis of two Caenorhabditis elegans kinesins KLP-6 and UNC-104 reveals a common and distinct activation mechanism in kinesin-3.

Kita T, Chiba K, Wang J, Nakagawa A, Niwa S. Kita T, et al. Among authors: niwa s. Elife. 2024 Jan 11;12:RP89040. doi: 10.7554/eLife.89040. Elife. 2024. PMID: 38206323 Free PMC article.

5

β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.

Niwa S, Takahashi H, Hirokawa N. Niwa S, et al. EMBO J. 2013 May 15;32(10):1352-64. doi: 10.1038/emboj.2013.59. Epub 2013 Mar 15. EMBO J. 2013. PMID: 23503589 Free PMC article.

6

A highly conserved 3₁₀ helix within the kinesin motor domain is critical for kinesin function and human health.

Lam AJ, Rao L, Anazawa Y, Okada K, Chiba K, Dacy M, Niwa S, Gennerich A, Nowakowski DW, McKenney RJ. Lam AJ, et al. Among authors: niwa s. Sci Adv. 2021 Apr 30;7(18):eabf1002. doi: 10.1126/sciadv.abf1002. Print 2021 Apr. Sci Adv. 2021. PMID: 33931448 Free PMC article.

7

An ALS-associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity.

Nakano J, Chiba K, Niwa S. Nakano J, et al. Among authors: niwa s. Genes Cells. 2022 Jun;27(6):421-435. doi: 10.1111/gtc.12936. Epub 2022 May 20. Genes Cells. 2022. PMID: 35430760 Free PMC article.

8

The nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegans.

Niwa S. Niwa S. Sci Rep. 2016 Aug 12;6:31544. doi: 10.1038/srep31544. Sci Rep. 2016. PMID: 27515926 Free PMC article.

9

Physical parameters describing neuronal cargo transport by kinesin UNC-104.

Hayashi K, Matsumoto S, Miyamoto MG, Niwa S. Hayashi K, et al. Among authors: niwa s. Biophys Rev. 2019 Jun;11(3):471-482. doi: 10.1007/s12551-019-00548-9. Epub 2019 May 21. Biophys Rev. 2019. PMID: 31115864 Free PMC article. Review.

10

The FHA domain is essential for autoinhibition of KIF1A/UNC-104 proteins.

Niwa S, Watanabe T, Chiba K. Niwa S, et al. J Cell Sci. 2024 Oct 1;137(19):jcs262017. doi: 10.1242/jcs.262017. Epub 2024 Oct 10. J Cell Sci. 2024. PMID: 39239883

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