Meanwell NA - Search Results

1

The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor.

Naidu BN, Walker MA, Sorenson ME, Ueda Y, Matiskella JD, Connolly TP, Dicker IB, Lin Z, Bollini S, Terry BJ, Higley H, Zheng M, Parker DD, Wu D, Adams S, Krystal MR, Meanwell NA. Naidu BN, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2124-2130. doi: 10.1016/j.bmcl.2018.05.027. Epub 2018 May 14. Bioorg Med Chem Lett. 2018. PMID: 29779976

2

Structure-activity relationships associated with 3,4,5-triphenyl-1H-pyrazole-1-nonanoic acid, a nonprostanoid prostacyclin mimetic.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Seiler SM. Meanwell NA, et al. J Med Chem. 1992 Jan 24;35(2):389-97. doi: 10.1021/jm00080a028. J Med Chem. 1992. PMID: 1370696

3

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.

Meanwell NA, Rosenfeld MJ, Trehan AK, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Zavoico GB, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3483-97. doi: 10.1021/jm00097a006. J Med Chem. 1992. PMID: 1404230

4

Nonprostanoid prostacyclin mimetics. 3. Structural variations of the diphenyl heterocycle moiety.

Meanwell NA, Rosenfeld MJ, Trehan AK, Romine JL, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3498-512. doi: 10.1021/jm00097a007. J Med Chem. 1992. PMID: 1404231

5

Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5- oxazolyl]phenoxy]acetic acid.

Meanwell NA, Romine JL, Rosenfeld MJ, Martin SW, Trehan AK, Wright JJ, Malley MF, Gougoutas JZ, Brassard CL, Buchanan JO, et al. Meanwell NA, et al. J Med Chem. 1993 Nov 26;36(24):3884-903. doi: 10.1021/jm00076a018. J Med Chem. 1993. PMID: 7504734

6

Azetidin-2-one derivatives as inhibitors of thrombin.

Han WT, Trehan AK, Wright JJ, Federici ME, Seiler SM, Meanwell NA. Han WT, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1123-43. doi: 10.1016/0968-0896(95)00101-l. Bioorg Med Chem. 1995. PMID: 7582985

7

Active site-directed thrombin inhibitors--II. Studies related to arginine/guanidine bioisosteres.

St Laurent DR, Balasubramanian N, Han WT, Trehan A, Federici ME, Meanwell NA, Wright JJ, Seiler SM. St Laurent DR, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1145-56. doi: 10.1016/0968-0896(95)00103-n. Bioorg Med Chem. 1995. PMID: 7582986

8

Inhibitors of blood platelet cAMP phosphodiesterase. 4. Structural variation of the side-chain terminus of water-soluble 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives.

Meanwell NA, Hewawasam P, Thomas JA, Wright JJ, Russell JW, Gamberdella M, Goldenberg HJ, Seiler SM, Zavoico GB. Meanwell NA, et al. J Med Chem. 1993 Oct 29;36(22):3251-64. doi: 10.1021/jm00074a005. J Med Chem. 1993. PMID: 8230115

9

Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted alpha to the oxazole ring.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Hartl KS, Zavoico GB, et al. Meanwell NA, et al. J Med Chem. 1993 Nov 26;36(24):3871-83. doi: 10.1021/jm00076a017. J Med Chem. 1993. PMID: 8254619

10

Active site-directed synthetic thrombin inhibitors: synthesis, in vitro and in vivo activity profile of BMY 44621 and analogs. An examination of the role of the amino group in the D-Phe-Pro-Arg-H series.

Balasubramanian N, St Laurent DR, Federici ME, Meanwell NA, Wright JJ, Schumacher WA, Seiler SM. Balasubramanian N, et al. Among authors: meanwell na. J Med Chem. 1993 Jan 22;36(2):300-3. doi: 10.1021/jm00054a018. J Med Chem. 1993. PMID: 8423602 No abstract available.

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