Woodruff TM - Search Results

1

Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.

Michailidou I, Jongejan A, Vreijling JP, Georgakopoulou T, de Wissel MB, Wolterman RA, Ruizendaal P, Klar-Mohamad N, Grootemaat AE, Picavet DI, Kumar V, van Kooten C, Woodruff TM, Morgan BP, van der Wel NN, Ramaglia V, Fluiter K, Baas F. Michailidou I, et al. Among authors: woodruff tm. Acta Neuropathol Commun. 2018 May 3;6(1):36. doi: 10.1186/s40478-018-0536-y. Acta Neuropathol Commun. 2018. PMID: 29724241 Free PMC article.

2

The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.

Woodruff TM, Costantini KJ, Crane JW, Atkin JD, Monk PN, Taylor SM, Noakes PG. Woodruff TM, et al. J Immunol. 2008 Dec 15;181(12):8727-34. doi: 10.4049/jimmunol.181.12.8727. J Immunol. 2008. PMID: 19050293

3

Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects.

Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeanes A, Woodruff TM. Denny KJ, et al. Among authors: woodruff tm. Birth Defects Res A Clin Mol Teratol. 2016 Mar;106(3):201-7. doi: 10.1002/bdra.23483. Epub 2016 Feb 22. Birth Defects Res A Clin Mol Teratol. 2016. PMID: 26900104 Free PMC article.

4

Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice.

Mantovani S, Gordon R, Li R, Christie DC, Kumar V, Woodruff TM. Mantovani S, et al. Among authors: woodruff tm. Hum Mol Genet. 2016 May 1;25(9):1780-91. doi: 10.1093/hmg/ddw050. Epub 2016 Feb 21. Hum Mol Genet. 2016. PMID: 26908618

5

Pharmacological inhibition of complement C5a-C5a₁ receptor signalling ameliorates disease pathology in the hSOD1^G93A mouse model of amyotrophic lateral sclerosis.

Lee JD, Kumar V, Fung JN, Ruitenberg MJ, Noakes PG, Woodruff TM. Lee JD, et al. Among authors: woodruff tm. Br J Pharmacol. 2017 Apr;174(8):689-699. doi: 10.1111/bph.13730. Epub 2017 Mar 3. Br J Pharmacol. 2017. PMID: 28128456 Free PMC article.

6

The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury.

Biggins PJC, Brennan FH, Taylor SM, Woodruff TM, Ruitenberg MJ. Biggins PJC, et al. Among authors: woodruff tm. J Neurotrauma. 2017 Jun 15;34(12):2075-2085. doi: 10.1089/neu.2016.4701. Epub 2017 Apr 26. J Neurotrauma. 2017. PMID: 28173736

7

Development and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice.

Kumar V, Lee JD, Clark RJ, Woodruff TM. Kumar V, et al. Among authors: woodruff tm. Sci Rep. 2018 May 25;8(1):8101. doi: 10.1038/s41598-018-26387-4. Sci Rep. 2018. PMID: 29802264 Free PMC article.

8

Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.

Tan SM, Ziemann M, Thallas-Bonke V, Snelson M, Kumar V, Laskowski A, Nguyen TV, Huynh K, Clarke MV, Libianto R, Baker ST, Skene A, Power DA, MacIsaac RJ, Henstridge DC, Wetsel RA, El-Osta A, Meikle PJ, Wilson SG, Forbes JM, Cooper ME, Ekinci EI, Woodruff TM, Coughlan MT. Tan SM, et al. Among authors: woodruff tm. Diabetes. 2020 Jan;69(1):83-98. doi: 10.2337/db19-0043. Epub 2019 Oct 17. Diabetes. 2020. PMID: 31624141

9

Preclinical Pharmacokinetics of Complement C5a Receptor Antagonists PMX53 and PMX205 in Mice.

Kumar V, Lee JD, Clark RJ, Noakes PG, Taylor SM, Woodruff TM. Kumar V, et al. Among authors: woodruff tm. ACS Omega. 2020 Jan 30;5(5):2345-2354. doi: 10.1021/acsomega.9b03735. eCollection 2020 Feb 11. ACS Omega. 2020. PMID: 32064396 Free PMC article.

10

A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models.

Kumar V, Lee JD, Coulson EJ, Woodruff TM. Kumar V, et al. Among authors: woodruff tm. J Neurochem. 2021 Aug;158(3):807-817. doi: 10.1111/jnc.15119. Epub 2020 Jul 22. J Neurochem. 2021. PMID: 32628780 Free article.

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