Packer MS - Search Results

1

Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Gaudelli NM, et al. Among authors: packer ms. Nature. 2018 Jul;559(7714):E8. doi: 10.1038/s41586-018-0070-x. Nature. 2018. PMID: 29720650

2

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Komor AC, et al. Among authors: packer ms. Nature. 2016 May 19;533(7603):420-4. doi: 10.1038/nature17946. Epub 2016 Apr 20. Nature. 2016. PMID: 27096365 Free PMC article.

3

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Gaudelli NM, et al. Among authors: packer ms. Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. Nature. 2017. PMID: 29160308 Free PMC article.

4

A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.

Dickinson BC, Packer MS, Badran AH, Liu DR. Dickinson BC, et al. Among authors: packer ms. Nat Commun. 2014 Oct 30;5:5352. doi: 10.1038/ncomms6352. Nat Commun. 2014. PMID: 25355134 Free PMC article.

5

Methods for the directed evolution of proteins.

Packer MS, Liu DR. Packer MS, et al. Nat Rev Genet. 2015 Jul;16(7):379-94. doi: 10.1038/nrg3927. Epub 2015 Jun 9. Nat Rev Genet. 2015. PMID: 26055155 Review.

6

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Kim YB, et al. Among authors: packer ms. Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13. Nat Biotechnol. 2017. PMID: 28191901 Free PMC article.

7

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Komor AC, et al. Among authors: packer ms. Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28875174 Free PMC article.

8

Phage-assisted continuous evolution of proteases with altered substrate specificity.

Packer MS, Rees HA, Liu DR. Packer MS, et al. Nat Commun. 2017 Oct 16;8(1):956. doi: 10.1038/s41467-017-01055-9. Nat Commun. 2017. PMID: 29038472 Free PMC article.

9

Directed evolution of adenine base editors with increased activity and therapeutic application.

Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G. Gaudelli NM, et al. Among authors: packer ms. Nat Biotechnol. 2020 Jul;38(7):892-900. doi: 10.1038/s41587-020-0491-6. Epub 2020 Apr 13. Nat Biotechnol. 2020. PMID: 32284586

10

Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation.

Chu SH, Packer M, Rees H, Lam D, Yu Y, Marshall J, Cheng LI, Lam D, Olins J, Ran FA, Liquori A, Gantzer B, Decker J, Born D, Barrera L, Hartigan A, Gaudelli N, Ciaramella G, Slaymaker IM. Chu SH, et al. CRISPR J. 2021 Apr;4(2):169-177. doi: 10.1089/crispr.2020.0144. CRISPR J. 2021. PMID: 33876959

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