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A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.
Bu P, Chen KY, Chen JH, Wang L, Walters J, Shin YJ, Goerger JP, Sun J, Witherspoon M, Rakhilin N, Li J, Yang H, Milsom J, Lee S, Zipfel W, Jin MM, Gümüş ZH, Lipkin SM, Shen X. Bu P, et al. Among authors: shen x. Cell Stem Cell. 2013 May 2;12(5):602-15. doi: 10.1016/j.stem.2013.03.002. Cell Stem Cell. 2013. PMID: 23642368 Free PMC article.
A metabolic signature of colon cancer initiating cells.
Chen KY, Liu X, Bu P, Lin CS, Rakhilin N, Locasale JW, Shen X. Chen KY, et al. Among authors: shen x. Annu Int Conf IEEE Eng Med Biol Soc. 2014;2014:4759-62. doi: 10.1109/EMBC.2014.6944688. Annu Int Conf IEEE Eng Med Biol Soc. 2014. PMID: 25571056 Free PMC article.
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.
Bu P, Wang L, Chen KY, Rakhilin N, Sun J, Closa A, Tung KL, King S, Kristine Varanko A, Xu Y, Huan Chen J, Zessin AS, Shealy J, Cummings B, Hsu D, Lipkin SM, Moreno V, Gümüş ZH, Shen X. Bu P, et al. Among authors: shen x. Nat Commun. 2015 Apr 15;6:6879. doi: 10.1038/ncomms7879. Nat Commun. 2015. PMID: 25872451 Free PMC article.
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Chen HJ, Sun J, Huang Z, Hou H Jr, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou XK, Edwards R, Chen J, Chen KY, Bu P, Wang L, Xu Y, Munroe R, Abratte C, Miller AD, Gümüş ZH, Shuler M, Nishimura N, Edelmann W, Shen X, Lipkin SM. Chen HJ, et al. Among authors: shen x. Nat Biotechnol. 2015 Jun;33(6):656-60. doi: 10.1038/nbt.3239. Epub 2015 May 25. Nat Biotechnol. 2015. PMID: 26006007 Free PMC article.
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