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Synthesis and optimization of peptidomimetics as HIV entry inhibitors against the receptor protein CD4 using STD NMR and ligand docking.
Neffe AT, Bilang M, Meyer B. Neffe AT, et al. Among authors: meyer b. Org Biomol Chem. 2006 Sep 7;4(17):3259-67. doi: 10.1039/b605380g. Epub 2006 Jul 26. Org Biomol Chem. 2006. PMID: 17036114
We recently described the design and synthesis of a novel CD4 binding peptidomimetic as a potential HIV entry inhibitor with a KD value of approximately 35 microM and a high proteolytic stability [A. T. Neffe and B. Meyer, Angew. Chem., Int. Ed., 2004, 43, 2937-2940 …
We recently described the design and synthesis of a novel CD4 binding peptidomimetic as a potential HIV entry inhibitor with a KD value of a …
3,419 results