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Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).
Welte T, Dellinger RP, Ebelt H, Ferrer M, Opal SM, Singer M, Vincent JL, Werdan K, Martin-Loeches I, Almirall J, Artigas A, Ignacio Ayestarán J, Nuding S, Ferrer R, Sirgo Rodríguez G, Shankar-Hari M, Álvarez-Lerma F, Riessen R, Sirvent JM, Kluge S, Zacharowski K, Bonastre Mora J, Lapp H, Wöbker G, Achtzehn U, Brealey D, Kempa A, Sánchez García M, Brederlau J, Kochanek M, Reschreiter HP, Wise MP, Belohradsky BH, Bobenhausen I, Dälken B, Dubovy P, Langohr P, Mayer M, Schüttrumpf J, Wartenberg-Demand A, Wippermann U, Wolf D, Torres A. Welte T, et al. Among authors: brealey d. Intensive Care Med. 2018 Apr;44(4):438-448. doi: 10.1007/s00134-018-5143-7. Epub 2018 Apr 9. Intensive Care Med. 2018. PMID: 29632995 Free PMC article. Clinical Trial.
Mitochondrial dysfunction in sepsis.
Singer M, Brealey D. Singer M, et al. Among authors: brealey d. Biochem Soc Symp. 1999;66:149-66. doi: 10.1042/bss0660149. Biochem Soc Symp. 1999. PMID: 10989665 Review.
Mitochondrial Dysfunction in Sepsis.
Brealey D, Singer M. Brealey D, et al. Curr Infect Dis Rep. 2003 Oct;5(5):365-371. doi: 10.1007/s11908-003-0015-9. Curr Infect Dis Rep. 2003. PMID: 13678565
Hyperglycemia in critical illness: a review.
Brealey D, Singer M. Brealey D, et al. J Diabetes Sci Technol. 2009 Nov 1;3(6):1250-60. doi: 10.1177/193229680900300604. J Diabetes Sci Technol. 2009. PMID: 20144378 Free PMC article. Review.
So you want to be ... a critical care physician.
Brealey DA, Singer M. Brealey DA, et al. Br J Hosp Med (Lond). 2010 Jun;71(6):M96. doi: 10.12968/hmed.2010.71.Sup6.48469. Br J Hosp Med (Lond). 2010. PMID: 20551887 No abstract available.
Another nail in the hammer's coffin?
Singer M, Brealey D. Singer M, et al. Among authors: brealey d. Crit Care. 2011 Aug 8;15(4):179. doi: 10.1186/cc10311. Crit Care. 2011. PMID: 21888684 Free PMC article.
122 results