Luo S - Search Results

1

Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes.

Song H, Li H, Guo S, Pan Y, Fu Y, Zhou Z, Li Z, Wen X, Sun X, He B, Gu H, Zhao Q, Wang C, An P, Luo S, Hu Y, Xie X, Lu B. Song H, et al. Among authors: luo s. Brain. 2018 Jun 1;141(6):1782-1798. doi: 10.1093/brain/awy081. Brain. 2018. PMID: 29608652 Free PMC article.

2

Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.

Yu M, Fu Y, Liang Y, Song H, Yao Y, Wu P, Yao Y, Pan Y, Wen X, Ma L, Hexige S, Ding Y, Luo S, Lu B. Yu M, et al. Among authors: luo s. Cell Res. 2017 Dec;27(12):1441-1465. doi: 10.1038/cr.2017.113. Epub 2017 Oct 13. Cell Res. 2017. PMID: 29151587 Free PMC article.

3

Conformation Polymorphism of Polyglutamine Proteins.

Feng X, Luo S, Lu B. Feng X, et al. Among authors: luo s. Trends Biochem Sci. 2018 Jun;43(6):424-435. doi: 10.1016/j.tibs.2018.03.002. Epub 2018 Apr 7. Trends Biochem Sci. 2018. PMID: 29636213 Review.

4

Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response.

Yang Y, Willis TL, Button RW, Strang CJ, Fu Y, Wen X, Grayson PRC, Evans T, Sipthorpe RJ, Roberts SL, Hu B, Zhang J, Lu B, Luo S. Yang Y, et al. Among authors: luo s. Nat Commun. 2019 Aug 21;10(1):3759. doi: 10.1038/s41467-019-11671-2. Nat Commun. 2019. PMID: 31434890 Free PMC article.

5

Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds.

Li Z, Wang C, Wang Z, Zhu C, Li J, Sha T, Ma L, Gao C, Yang Y, Sun Y, Wang J, Sun X, Lu C, Difiglia M, Mei Y, Ding C, Luo S, Dang Y, Ding Y, Fei Y, Lu B. Li Z, et al. Among authors: luo s. Nature. 2019 Nov;575(7781):203-209. doi: 10.1038/s41586-019-1722-1. Epub 2019 Oct 30. Nature. 2019. PMID: 31666698

6

Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease.

Valionyte E, Yang Y, Roberts SL, Kelly J, Lu B, Luo S. Valionyte E, et al. Among authors: luo s. J Mol Biol. 2020 Apr 3;432(8):2673-2691. doi: 10.1016/j.jmb.2019.11.012. Epub 2019 Nov 29. J Mol Biol. 2020. PMID: 31786267 Review.

7

Bim contributes to the progression of Huntington's disease-associated phenotypes.

Roberts SL, Evans T, Yang Y, Fu Y, Button RW, Sipthorpe RJ, Cowan K, Valionyte E, Anichtchik O, Li H, Lu B, Luo S. Roberts SL, et al. Among authors: luo s. Hum Mol Genet. 2020 Jan 15;29(2):216-227. doi: 10.1093/hmg/ddz275. Hum Mol Genet. 2020. PMID: 31813995

8

Degradation of lipid droplets by chimeric autophagy-tethering compounds.

Fu Y, Chen N, Wang Z, Luo S, Ding Y, Lu B. Fu Y, et al. Among authors: luo s. Cell Res. 2021 Sep;31(9):965-979. doi: 10.1038/s41422-021-00532-7. Epub 2021 Jul 8. Cell Res. 2021. PMID: 34239073 Free PMC article.

9

The caspase-6-p62 axis modulates p62 droplets based autophagy in a dominant-negative manner.

Valionyte E, Yang Y, Griffiths SA, Bone AT, Barrow ER, Sharma V, Lu B, Luo S. Valionyte E, et al. Among authors: luo s. Cell Death Differ. 2022 Jun;29(6):1211-1227. doi: 10.1038/s41418-021-00912-x. Epub 2021 Dec 3. Cell Death Differ. 2022. PMID: 34862482 Free PMC article.

10

Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis.

Pan Y, Lu J, Feng X, Lu S, Yang Y, Yang G, Tan S, Wang L, Li P, Luo S, Lu B. Pan Y, et al. Among authors: luo s. Nat Chem Biol. 2023 Nov;19(11):1372-1383. doi: 10.1038/s41589-023-01384-5. Epub 2023 Aug 17. Nat Chem Biol. 2023. PMID: 37592155

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