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Page 1
A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions.
Eraña H, Sampedro-Torres-Quevedo C, Charco JM, Díaz-Domínguez CM, Peccati F, San-Juan-Ansoleaga M, Vidal E, Gonçalves-Anjo N, Pérez-Castro MA, González-Miranda E, Piñeiro P, Fernández-Veiga L, Galarza-Ahumada J, Fernández-Muñoz E, Perez de Nanclares G, Telling G, Geijo M, Jiménez-Osés G, Castilla J. Eraña H, et al. Among authors: perez castro ma. Nat Commun. 2024 Mar 8;15(1):2112. doi: 10.1038/s41467-024-46360-2. Nat Commun. 2024. PMID: 38459071 Free PMC article.
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.
Eraña H, Díaz-Domínguez CM, Charco JM, Vidal E, González-Miranda E, Pérez-Castro MA, Piñeiro P, López-Moreno R, Sampedro-Torres-Quevedo C, Fernández-Veiga L, Tasis-Galarza J, Lorenzo NL, Santini-Santiago A, Lázaro M, García-Martínez S, Gonçalves-Anjo N, San-Juan-Ansoleaga M, Galarza-Ahumada J, Fernández-Muñoz E, Giler S, Valle M, Telling GC, Geijó M, Requena JR, Castilla J. Eraña H, et al. Among authors: perez castro ma. Acta Neuropathol Commun. 2023 Sep 7;11(1):145. doi: 10.1186/s40478-023-01640-8. Acta Neuropathol Commun. 2023. PMID: 37679832 Free PMC article.
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.
Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, Geijo M, Ordóñez M, Cantero G, di Bari M, Lorenzo NL, Pirisinu L, d'Agostino C, Torres JM, Béringue V, Telling G, Badiola JJ, Pumarola M, Bolea R, Nonno R, Requena JR, Castilla J. Vidal E, et al. Among authors: perez castro ma. Acta Neuropathol Commun. 2022 Dec 13;10(1):179. doi: 10.1186/s40478-022-01477-7. Acta Neuropathol Commun. 2022. PMID: 36514160 Free PMC article.
Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases.
Eraña H, Charco JM, González-Miranda E, García-Martínez S, López-Moreno R, Pérez-Castro MA, Díaz-Domínguez CM, García-Salvador A, Castilla J. Eraña H, et al. Among authors: perez castro ma. Biomolecules. 2020 Mar 19;10(3):469. doi: 10.3390/biom10030469. Biomolecules. 2020. PMID: 32204429 Free PMC article. Review.
Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein.
Vidal E, Fernández-Borges N, Eraña H, Parra B, Pintado B, Sánchez-Martín MA, Charco JM, Ordóñez M, Pérez-Castro MA, Pumarola M, Mathiason CK, Mayoral T, Castilla J. Vidal E, et al. Among authors: perez castro ma. FASEB J. 2020 Mar;34(3):3969-3982. doi: 10.1096/fj.201902646R. Epub 2020 Jan 15. FASEB J. 2020. PMID: 31944411
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies.
Eraña H, Charco JM, Di Bari MA, Díaz-Domínguez CM, López-Moreno R, Vidal E, González-Miranda E, Pérez-Castro MA, García-Martínez S, Bravo S, Fernández-Borges N, Geijo M, D'Agostino C, Garrido J, Bian J, König A, Uluca-Yazgi B, Sabate R, Khaychuk V, Vanni I, Telling GC, Heise H, Nonno R, Requena JR, Castilla J. Eraña H, et al. Among authors: perez castro ma. PLoS Pathog. 2019 Oct 23;15(10):e1008117. doi: 10.1371/journal.ppat.1008117. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31644574 Free PMC article.
HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System.
Bachiller S, Roca-Ceballos MA, García-Domínguez I, Pérez-Villegas EM, Martos-Carmona D, Pérez-Castro MÁ, Real LM, Rosa JL, Tabares L, Venero JL, Armengol JÁ, Carrión ÁM, Ruiz R. Bachiller S, et al. Among authors: perez castro ma. Mol Neurobiol. 2018 Dec;55(12):8856-8868. doi: 10.1007/s12035-018-1021-0. Epub 2018 Mar 30. Mol Neurobiol. 2018. PMID: 29603094
11 results