Sashital DG - Search Results

1

Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.

Lee H, Zhou Y, Taylor DW, Sashital DG. Lee H, et al. Among authors: sashital dg. Mol Cell. 2018 Apr 5;70(1):48-59.e5. doi: 10.1016/j.molcel.2018.03.003. Epub 2018 Mar 27. Mol Cell. 2018. PMID: 29602742 Free PMC article.

2

Mechanism of foreign DNA selection in a bacterial adaptive immune system.

Sashital DG, Wiedenheft B, Doudna JA. Sashital DG, et al. Mol Cell. 2012 Jun 8;46(5):606-15. doi: 10.1016/j.molcel.2012.03.020. Epub 2012 Apr 19. Mol Cell. 2012. PMID: 22521690 Free PMC article.

3

CRISPR interference and priming varies with individual spacer sequences.

Xue C, Seetharam AS, Musharova O, Severinov K, Brouns SJ, Severin AJ, Sashital DG. Xue C, et al. Among authors: sashital dg. Nucleic Acids Res. 2015 Dec 15;43(22):10831-47. doi: 10.1093/nar/gkv1259. Epub 2015 Nov 19. Nucleic Acids Res. 2015. PMID: 26586800 Free PMC article.

4

Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity.

Xue C, Whitis NR, Sashital DG. Xue C, et al. Among authors: sashital dg. Mol Cell. 2016 Nov 17;64(4):826-834. doi: 10.1016/j.molcel.2016.09.033. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871367 Free PMC article.

5

Prokaryotic Argonaute Uses an All-in-One Mechanism to Provide Host Defense.

Sashital DG. Sashital DG. Mol Cell. 2017 Mar 16;65(6):957-958. doi: 10.1016/j.molcel.2017.03.002. Mol Cell. 2017. PMID: 28306508 Free article.

6

The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit.

Murugan K, Babu K, Sundaresan R, Rajan R, Sashital DG. Murugan K, et al. Among authors: sashital dg. Mol Cell. 2017 Oct 5;68(1):15-25. doi: 10.1016/j.molcel.2017.09.007. Mol Cell. 2017. PMID: 28985502 Free PMC article. Review.

7

Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade.

Xue C, Zhu Y, Zhang X, Shin YK, Sashital DG. Xue C, et al. Among authors: sashital dg. Cell Rep. 2017 Dec 26;21(13):3717-3727. doi: 10.1016/j.celrep.2017.11.110. Cell Rep. 2017. PMID: 29281822 Free PMC article.

8

Pathogen detection in the CRISPR-Cas era.

Sashital DG. Sashital DG. Genome Med. 2018 Apr 24;10(1):32. doi: 10.1186/s13073-018-0543-4. Genome Med. 2018. PMID: 29690921 Free PMC article. Review.

9

CRISPR-Cas molecular beacons as tool for studies of assembly of CRISPR-Cas effector complexes and their interactions with DNA.

Mekler V, Kuznedelov K, Minakhin L, Murugan K, Sashital DG, Severinov K. Mekler V, et al. Among authors: sashital dg. Methods Enzymol. 2019;616:337-363. doi: 10.1016/bs.mie.2018.10.026. Epub 2018 Dec 1. Methods Enzymol. 2019. PMID: 30691650 Free PMC article.

10

Fluorescence-based methods for measuring target interference by CRISPR-Cas systems.

Phan PT, Schelling M, Xue C, Sashital DG. Phan PT, et al. Among authors: sashital dg. Methods Enzymol. 2019;616:61-85. doi: 10.1016/bs.mie.2018.10.027. Epub 2018 Dec 21. Methods Enzymol. 2019. PMID: 30691655 Free PMC article.

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