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Histone demethylase KDM5B is a key regulator of genome stability.
Li X, Liu L, Yang S, Song N, Zhou X, Gao J, Yu N, Shan L, Wang Q, Liang J, Xuan C, Wang Y, Shang Y, Shi L. Li X, et al. Among authors: liu l. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7096-101. doi: 10.1073/pnas.1324036111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778210 Free PMC article.
Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis.
Wang Q, Ma S, Song N, Li X, Liu L, Yang S, Ding X, Shan L, Zhou X, Su D, Wang Y, Zhang Q, Liu X, Yu N, Zhang K, Shang Y, Yao Z, Shi L. Wang Q, et al. Among authors: liu x, liu l. J Clin Invest. 2016 Jun 1;126(6):2205-20. doi: 10.1172/JCI85747. Epub 2016 May 16. J Clin Invest. 2016. PMID: 27183383 Free PMC article.
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Li X, Song N, Liu L, Liu X, Ding X, Song X, Yang S, Shan L, Zhou X, Su D, Wang Y, Zhang Q, Cao C, Ma S, Yu N, Yang F, Wang Y, Yao Z, Shang Y, Shi L. Li X, et al. Among authors: liu x, liu l. Nat Commun. 2017 Mar 31;8:14866. doi: 10.1038/ncomms14866. Nat Commun. 2017. PMID: 28361952 Free PMC article.
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Song N, Cao C, Tang Y, Bi L, Jiang Y, Zhou Y, Song X, Liu L, Ge W. Song N, et al. Among authors: liu l. J Cell Physiol. 2018 Mar;233(3):2366-2377. doi: 10.1002/jcp.26108. Epub 2017 Sep 4. J Cell Physiol. 2018. PMID: 28722108
USP7 Deubiquitinates and Stabilizes SIRT1.
Song N, Cao C, Tian S, Long M, Liu L. Song N, et al. Among authors: liu l. Anat Rec (Hoboken). 2020 May;303(5):1337-1345. doi: 10.1002/ar.24252. Epub 2019 Oct 21. Anat Rec (Hoboken). 2020. PMID: 31502386 Free article.
A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.
Zhang Q, Cao C, Gong W, Bao K, Wang Q, Wang Y, Bi L, Ma S, Zhao J, Liu L, Tian S, Zhang K, Yang J, Yao Z, Song N, Shi L. Zhang Q, et al. Among authors: liu l. Theranostics. 2020 Aug 29;10(23):10769-10790. doi: 10.7150/thno.46878. eCollection 2020. Theranostics. 2020. PMID: 32929379 Free PMC article.
PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability.
Ma S, Cao C, Che S, Wang Y, Su D, Liu S, Gong W, Liu L, Sun J, Zhao J, Wang Q, Song N, Ge T, Guo Q, Tian S, Chen CD, Zhang T, Wang J, Ding X, Yang F, Ying G, Yang J, Zhang K, Zhu Y, Yao Z, Yang N, Shi L. Ma S, et al. Among authors: liu l, liu s. Sci Adv. 2021 May 5;7(19):eabf7684. doi: 10.1126/sciadv.abf7684. Print 2021 May. Sci Adv. 2021. PMID: 33952527 Free PMC article.
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