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Page 1
Sulfoximines as potent RORγ inverse agonists.
Ouvry G, Bihl F, Bouix-Peter C, Christin O, Defoin-Platel C, Deret S, Feret C, Froude D, Hacini-Rachinel F, Harris CS, Hervouet C, Lafitte G, Luzy AP, Musicki B, Orfila D, Parnet V, Pascau C, Pascau J, Pierre R, Raffin C, Rossio P, Spiesse D, Taquet N, Thoreau E, Vatinel R, Vial E, Hennequin LF. Ouvry G, et al. Among authors: orfila d. Bioorg Med Chem Lett. 2018 May 1;28(8):1269-1273. doi: 10.1016/j.bmcl.2018.03.041. Epub 2018 Mar 17. Bioorg Med Chem Lett. 2018. PMID: 29571573
Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists.
Ouvry G, Bouix-Peter C, Ciesielski F, Chantalat L, Christin O, Comino C, Duvert D, Feret C, Harris CS, Lamy L, Luzy AP, Musicki B, Orfila D, Pascau J, Parnet V, Perrin A, Pierre R, Polge G, Raffin C, Rival Y, Taquet N, Thoreau E, Hennequin LF. Ouvry G, et al. Among authors: orfila d. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5802-5808. doi: 10.1016/j.bmcl.2016.10.023. Epub 2016 Oct 12. Bioorg Med Chem Lett. 2016. PMID: 27815118
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis.
Ouvry G, Atrux-Tallau N, Bihl F, Bondu A, Bouix-Peter C, Carlavan I, Christin O, Cuadrado MJ, Defoin-Platel C, Deret S, Duvert D, Feret C, Forissier M, Fournier JF, Froude D, Hacini-Rachinel F, Harris CS, Hervouet C, Huguet H, Lafitte G, Luzy AP, Musicki B, Orfila D, Ozello B, Pascau C, Pascau J, Parnet V, Peluchon G, Pierre R, Piwnica D, Raffin C, Rossio P, Spiesse D, Taquet N, Thoreau E, Vatinel R, Vial E, Hennequin LF. Ouvry G, et al. Among authors: orfila d. ChemMedChem. 2018 Feb 20;13(4):321-337. doi: 10.1002/cmdc.201700758. Epub 2018 Feb 6. ChemMedChem. 2018. PMID: 29327456
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne.
Fournier JF, Clary L, Chambon S, Dumais L, Harris CS, Millois C, Pierre R, Talano S, Thoreau É, Aubert J, Aurelly M, Bouix-Peter C, Brethon A, Chantalat L, Christin O, Comino C, El-Bazbouz G, Ghilini AL, Isabet T, Lardy C, Luzy AP, Mathieu C, Mebrouk K, Orfila D, Pascau J, Reverse K, Roche D, Rodeschini V, Hennequin LF. Fournier JF, et al. Among authors: orfila d. J Med Chem. 2018 May 10;61(9):4030-4051. doi: 10.1021/acs.jmedchem.8b00067. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29648825
International consensus on Vibrant Soundbridge® implantation in children and adolescents.
Cremers CW, O'Connor AF, Helms J, Roberson J, Clarós P, Frenzel H, Profant M, Schmerber S, Streitberger C, Baumgartner WD, Orfila D, Pringle M, Cenjor C, Giarbini N, Jiang D, Snik AF. Cremers CW, et al. Among authors: orfila d. Int J Pediatr Otorhinolaryngol. 2010 Nov;74(11):1267-9. doi: 10.1016/j.ijporl.2010.07.028. Epub 2010 Sep 15. Int J Pediatr Otorhinolaryngol. 2010. PMID: 20828837
Facial nerve neurinoma in a child.
Chinski A, Orfila D, Perata H, Lubochiner LJ, Bensur D, Romano Luna MF. Chinski A, et al. Among authors: orfila d. Int J Pediatr Otorhinolaryngol. 1997 Jun 20;40(2-3):203-10. doi: 10.1016/s0165-5876(97)00043-8. Int J Pediatr Otorhinolaryngol. 1997. PMID: 9225189