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Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Červenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vaňourková Z, Alánová P, Kolář F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckář J. Červenka L, et al. Among authors: hammock bd. J Hypertens. 2018 Jun;36(6):1326-1341. doi: 10.1097/HJH.0000000000001708. J Hypertens. 2018. PMID: 29570510 Free PMC article.
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition.
Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD. Larsen BT, et al. Among authors: hammock bd. Am J Physiol Heart Circ Physiol. 2006 Feb;290(2):H491-9. doi: 10.1152/ajpheart.00927.2005. Epub 2005 Oct 28. Am J Physiol Heart Circ Physiol. 2006. PMID: 16258029 Free PMC article.
Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.
Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim IH, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld AJ, Collen D, Busse R, Janssens S. Pokreisz P, et al. Among authors: hammock bd. Hypertension. 2006 Apr;47(4):762-70. doi: 10.1161/01.HYP.0000208299.62535.58. Epub 2006 Feb 27. Hypertension. 2006. PMID: 16505204 Free PMC article.
1,127 results