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Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.
Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, Cheng Z, Højlund K, Wojtaszewski JFP, Yang X, Hulver MW, Helm RF, Treebak JT, Gerrard DE. Shi H, et al. Among authors: munk a. Mol Metab. 2018 May;11:160-177. doi: 10.1016/j.molmet.2018.02.010. Epub 2018 Feb 24. Mol Metab. 2018. PMID: 29525407 Free PMC article.
The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones.
Rudenko O, Shang J, Munk A, Ekberg JP, Petersen N, Engelstoft MS, Egerod KL, Hjorth SA, Wu M, Feng Y, Zhou YP, Mokrosinski J, Thams P, Reimann F, Gribble F, Rehfeld JF, Holst JJ, Treebak JT, Howard AD, Schwartz TW. Rudenko O, et al. Among authors: munk a. Mol Metab. 2019 Jan;19:49-64. doi: 10.1016/j.molmet.2018.10.012. Epub 2018 Nov 5. Mol Metab. 2019. PMID: 30472415 Free PMC article.
OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance.
Yang Y, Li X, Luan HH, Zhang B, Zhang K, Nam JH, Li Z, Fu M, Munk A, Zhang D, Wang S, Liu Y, Albuquerque JP, Ong Q, Li R, Wang Q, Robert ME, Perry RJ, Chung D, Shulman GI, Yang X. Yang Y, et al. Among authors: munk a. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16616-16625. doi: 10.1073/pnas.1916121117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601203 Free PMC article.
151 results