Kaplowitz N - Search Results

1

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice.

Gong S, Lan T, Zeng L, Luo H, Yang X, Li N, Chen X, Liu Z, Li R, Win S, Liu S, Zhou H, Schnabl B, Jiang Y, Kaplowitz N, Chen P. Gong S, et al. Among authors: kaplowitz n. J Hepatol. 2018 Jul;69(1):51-59. doi: 10.1016/j.jhep.2018.02.024. Epub 2018 Mar 8. J Hepatol. 2018. PMID: 29524531 Free PMC article.

2

c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.

Win S, Than TA, Min RW, Aghajan M, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. Hepatology. 2016 Jun;63(6):1987-2003. doi: 10.1002/hep.28486. Epub 2016 Mar 15. Hepatology. 2016. PMID: 26845758 Free PMC article.

3

Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice.

Niu M, Luo Z, Gong S, Win S, Kaplowitz N, Jiang Y, Chen P. Niu M, et al. Among authors: kaplowitz n. Am J Pathol. 2020 Jan;190(1):57-67. doi: 10.1016/j.ajpath.2019.09.009. Epub 2019 Oct 11. Am J Pathol. 2020. PMID: 31610172 Free PMC article.

4

Acetaminophen Hepatotoxicity: Strong Offense and Weakened Defense.

Kaplowitz N, Than TA, Win S. Kaplowitz N, et al. Hepatology. 2020 May;71(5):1530-1532. doi: 10.1002/hep.31189. Hepatology. 2020. PMID: 32065403 No abstract available.

5

Gut Microbiota and Liver Injury (I)-Acute Liver Injury.

Wu G, Win S, Than TA, Chen P, Kaplowitz N. Wu G, et al. Among authors: kaplowitz n. Adv Exp Med Biol. 2020;1238:23-37. doi: 10.1007/978-981-15-2385-4_3. Adv Exp Med Biol. 2020. PMID: 32323178 Review.

6

Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.

Shinohara M, Ybanez MD, Win S, Than TA, Jain S, Gaarde WA, Han D, Kaplowitz N. Shinohara M, et al. Among authors: kaplowitz n. J Biol Chem. 2010 Mar 12;285(11):8244-55. doi: 10.1074/jbc.M109.054999. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061376 Free PMC article.

7

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice.

Win S, Than TA, Han D, Petrovic LM, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. J Biol Chem. 2011 Oct 7;286(40):35071-8. doi: 10.1074/jbc.M111.276089. Epub 2011 Aug 15. J Biol Chem. 2011. PMID: 21844199 Free PMC article.

8

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria.

Han D, Dara L, Win S, Than TA, Yuan L, Abbasi SQ, Liu ZX, Kaplowitz N. Han D, et al. Among authors: kaplowitz n. Trends Pharmacol Sci. 2013 Apr;34(4):243-53. doi: 10.1016/j.tips.2013.01.009. Epub 2013 Feb 28. Trends Pharmacol Sci. 2013. PMID: 23453390 Free PMC article. Review.

9

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.

Win S, Than TA, Le BH, García-Ruiz C, Fernandez-Checa JC, Kaplowitz N. Win S, et al. Among authors: kaplowitz n. J Hepatol. 2015 Jun;62(6):1367-74. doi: 10.1016/j.jhep.2015.01.032. Epub 2015 Feb 7. J Hepatol. 2015. PMID: 25666017 Free PMC article.

10

Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity.

Kaplowitz N, Win S, Than TA, Liu ZX, Dara L. Kaplowitz N, et al. J Hepatol. 2015 Jul;63(1):5-7. doi: 10.1016/j.jhep.2015.02.050. Epub 2015 Mar 12. J Hepatol. 2015. PMID: 25770661 Free article. No abstract available.

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