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Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo.
Mycielska ME, Dettmer K, Rümmele P, Schmidt K, Prehn C, Milenkovic VM, Jagla W, Madej GM, Lantow M, Schladt M, Cecil A, Koehl GE, Eggenhofer E, Wachsmuth CJ, Ganapathy V, Schlitt HJ, Kunzelmann K, Ziegler C, Wetzel CH, Gaumann A, Lang SA, Adamski J, Oefner PJ, Geissler EK. Mycielska ME, et al. Among authors: gaumann a. Cancer Res. 2018 May 15;78(10):2513-2523. doi: 10.1158/0008-5472.CAN-17-2959. Epub 2018 Mar 6. Cancer Res. 2018. PMID: 29510993
Extracellular Citrate Fuels Cancer Cell Metabolism and Growth.
Haferkamp S, Drexler K, Federlin M, Schlitt HJ, Berneburg M, Adamski J, Gaumann A, Geissler EK, Ganapathy V, Parkinson EK, Mycielska ME. Haferkamp S, et al. Among authors: gaumann a. Front Cell Dev Biol. 2020 Dec 4;8:602476. doi: 10.3389/fcell.2020.602476. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33425906 Free PMC article. Review.
Potential Involvement of Extracellular Citrate in Brain Tumor Progression.
Jordan K, Stanton EH, Milenkovic VM, Federlin M, Drexler K, Buchalla W, Gaumann A, Adamski J, Proescholdt M, Haferkamp S, Geissler EK, Mycielska ME. Jordan K, et al. Among authors: gaumann a. Curr Mol Med. 2022;22(6):506-513. doi: 10.2174/1566524021666210302143802. Curr Mol Med. 2022. PMID: 33653247 Review.
Cancer-associated cells release citrate to support tumour metastatic progression.
Drexler K, Schmidt KM, Jordan K, Federlin M, Milenkovic VM, Liebisch G, Artati A, Schmidl C, Madej G, Tokarz J, Cecil A, Jagla W, Haerteis S, Aung T, Wagner C, Kolodziejczyk M, Heinke S, Stanton EH, Schwertner B, Riegel D, Wetzel CH, Buchalla W, Proescholdt M, Klein CA, Berneburg M, Schlitt HJ, Brabletz T, Ziegler C, Parkinson EK, Gaumann A, Geissler EK, Adamski J, Haferkamp S, Mycielska ME. Drexler K, et al. Among authors: gaumann a. Life Sci Alliance. 2021 Mar 23;4(6):e202000903. doi: 10.26508/lsa.202000903. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33758075 Free PMC article.
Extracellular citrate and metabolic adaptations of cancer cells.
Parkinson EK, Adamski J, Zahn G, Gaumann A, Flores-Borja F, Ziegler C, Mycielska ME. Parkinson EK, et al. Among authors: gaumann a. Cancer Metastasis Rev. 2021 Dec;40(4):1073-1091. doi: 10.1007/s10555-021-10007-1. Epub 2021 Dec 21. Cancer Metastasis Rev. 2021. PMID: 34932167 Free PMC article. Review.
Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.
Lang SA, Moser C, Gaumann A, Klein D, Glockzin G, Popp FC, Dahlke MH, Piso P, Schlitt HJ, Geissler EK, Stoeltzing O. Lang SA, et al. Among authors: gaumann a. Clin Cancer Res. 2007 Nov 1;13(21):6459-68. doi: 10.1158/1078-0432.CCR-07-1104. Clin Cancer Res. 2007. PMID: 17975158
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Moser C, Lang SA, Kainz S, Gaumann A, Fichtner-Feigl S, Koehl GE, Schlitt HJ, Geissler EK, Stoeltzing O. Moser C, et al. Among authors: gaumann a. Mol Cancer Ther. 2007 Nov;6(11):2868-78. doi: 10.1158/1535-7163.MCT-07-0410. Mol Cancer Ther. 2007. PMID: 18025273
89 results