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Page 1
HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.
de Bock CE, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O, Vandepoel R, Vicente C, Vanden Bempt M, Dagklis A, Geerdens E, Bornschein S, Gijsbers R, Soulier J, Meijerink JP, Heinäniemi M, Teppo S, Bouvy-Liivrand M, Lohi O, Radaelli E, Cools J. de Bock CE, et al. Among authors: dagklis a. Cancer Discov. 2018 May;8(5):616-631. doi: 10.1158/2159-8290.CD-17-0583. Epub 2018 Mar 1. Cancer Discov. 2018. PMID: 29496663
Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.
Dagklis A, Pauwels D, Lahortiga I, Geerdens E, Bittoun E, Cauwelier B, Tousseyn T, Uyttebroeck A, Maertens J, Verhoef G, Vandenberghe P, Cools J. Dagklis A, et al. Haematologica. 2015 Mar;100(3):e102-5. doi: 10.3324/haematol.2014.119248. Epub 2014 Dec 19. Haematologica. 2015. PMID: 25527561 Free PMC article. No abstract available.
The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia.
Vercruysse T, De Bie J, Neggers JE, Jacquemyn M, Vanstreels E, Schmid-Burgk JL, Hornung V, Baloglu E, Landesman Y, Senapedis W, Shacham S, Dagklis A, Cools J, Daelemans D. Vercruysse T, et al. Among authors: dagklis a. Clin Cancer Res. 2017 May 15;23(10):2528-2541. doi: 10.1158/1078-0432.CCR-16-1580. Epub 2016 Oct 25. Clin Cancer Res. 2017. PMID: 27780859
HS1 has a central role in the trafficking and homing of leukemic B cells.
Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, Muzio M, Caiolfa V, Kitamura D, Restuccia U, Bachi A, Rocchi M, Ponzoni M, Ghia P, Caligaris-Cappio F. Scielzo C, et al. Among authors: dagklis a. Blood. 2010 Nov 4;116(18):3537-46. doi: 10.1182/blood-2009-12-258814. Epub 2010 Jun 8. Blood. 2010. PMID: 20530793 Free article.
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P. Simonetti G, et al. Among authors: dagklis a. Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23. Haematologica. 2014. PMID: 24859880 Free PMC article.
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.
Bertilaccio MT, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, Mantovani A, Ponzoni M, Ghia P, Garlanda C, Caligaris-Cappio F, Muzio M. Bertilaccio MT, et al. Among authors: dagklis a. Blood. 2011 Jul 21;118(3):660-9. doi: 10.1182/blood-2011-01-329870. Epub 2011 Jun 7. Blood. 2011. PMID: 21652674 Free article.
General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL.
Fazi C, Scarfò L, Pecciarini L, Cottini F, Dagklis A, Janus A, Talarico A, Scielzo C, Sala C, Toniolo D, Caligaris-Cappio F, Ghia P. Fazi C, et al. Among authors: dagklis a. Blood. 2011 Dec 15;118(25):6618-25. doi: 10.1182/blood-2011-05-357251. Epub 2011 Aug 29. Blood. 2011. PMID: 21876118 Free article.
25 results