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Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1.
Varnes JG, Xiong H, Forst JM, Holmquist CR, Ernst GE, Frietze W, Dembofsky B, Andisik DW, Palmer WE, Hinkley L, Steelman GB, Wilkins DE, Tian G, Jonak G, Potts WM, Wang X, Brugel TA, Alhambra C, Wood MW, Veale CA, Albert JS. Varnes JG, et al. Among authors: alhambra c. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1043-1049. doi: 10.1016/j.bmcl.2018.02.029. Epub 2018 Feb 14. Bioorg Med Chem Lett. 2018. PMID: 29486970
2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.
Brown DG, Maier DL, Sylvester MA, Hoerter TN, Menhaji-Klotz E, Lasota CC, Hirata LT, Wilkins DE, Scott CW, Trivedi S, Chen T, McCarthy DJ, Maciag CM, Sutton EJ, Cumberledge J, Mathisen D, Roberts J, Gupta A, Liu F, Elmore CS, Alhambra C, Krumrine JR, Wang X, Ciaccio PJ, Wood MW, Campbell JB, Johansson MJ, Xia J, Wen X, Jiang J, Wang X, Peng Z, Hu T, Wang J. Brown DG, et al. Among authors: alhambra c. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3399-403. doi: 10.1016/j.bmcl.2011.03.117. Epub 2011 Apr 8. Bioorg Med Chem Lett. 2011. PMID: 21524576
Development and SAR of functionally selective allosteric modulators of GABAA receptors.
Alhambra C, Becker C, Blake T, Chang AH, Damewood JR Jr, Daniels T, Dembofsky BT, Gurley DA, Hall JE, Herzog KJ, Horchler CL, Ohnmacht CJ, Schmiesing RJ, Dudley A, Ribadeneira MD, Knappenberger KS, Maciag C, Stein MM, Chopra M, Liu XF, Christian EP, Arriza JL, Chapdelaine MJ. Alhambra C, et al. Bioorg Med Chem. 2011 May 1;19(9):2927-38. doi: 10.1016/j.bmc.2011.03.035. Epub 2011 Mar 29. Bioorg Med Chem. 2011. PMID: 21498079
Systems Genetics Identifies a Novel Regulatory Domain of Amylose Synthesis.
Butardo VM Jr, Anacleto R, Parween S, Samson I, de Guzman K, Alhambra CM, Misra G, Sreenivasulu N. Butardo VM Jr, et al. Among authors: alhambra cm. Plant Physiol. 2017 Jan;173(1):887-906. doi: 10.1104/pp.16.01248. Epub 2016 Nov 23. Plant Physiol. 2017. PMID: 27881726 Free PMC article.
16 results