Fan Z - Search Results

1

Tau protein liquid-liquid phase separation can initiate tau aggregation.

Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT. Wegmann S, et al. Among authors: fan z. EMBO J. 2018 Apr 3;37(7):e98049. doi: 10.15252/embj.201798049. Epub 2018 Feb 22. EMBO J. 2018. PMID: 29472250 Free PMC article.

2

Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease.

McFarland NR, Fan Z, Xu K, Schwarzschild MA, Feany MB, Hyman BT, McLean PJ. McFarland NR, et al. Among authors: fan z. J Neuropathol Exp Neurol. 2009 May;68(5):515-24. doi: 10.1097/NEN.0b013e3181a24b53. J Neuropathol Exp Neurol. 2009. PMID: 19525899 Free PMC article.

3

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.

Stoothoff W, Jones PB, Spires-Jones TL, Joyner D, Chhabra E, Bercury K, Fan Z, Xie H, Bacskai B, Edd J, Irimia D, Hyman BT. Stoothoff W, et al. Among authors: fan z. J Neurochem. 2009 Oct;111(2):417-27. doi: 10.1111/j.1471-4159.2009.06316.x. Epub 2009 Aug 3. J Neurochem. 2009. PMID: 19686388 Free PMC article.

4

Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.

Uemura K, Lill CM, Li X, Peters JA, Ivanov A, Fan Z, DeStrooper B, Bacskai BJ, Hyman BT, Berezovska O. Uemura K, et al. Among authors: fan z. PLoS One. 2009 Nov 18;4(11):e7893. doi: 10.1371/journal.pone.0007893. PLoS One. 2009. PMID: 19924286 Free PMC article.

5

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.

Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkalne A, Fan Z, Spires-Jones T, Xie H, Arbel-Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT. Wu HY, et al. Among authors: fan z. J Neurosci. 2010 Feb 17;30(7):2636-49. doi: 10.1523/JNEUROSCI.4456-09.2010. J Neurosci. 2010. PMID: 20164348 Free PMC article.

6

Characterization of oligomer formation of amyloid-beta peptide using a split-luciferase complementation assay.

Hashimoto T, Adams KW, Fan Z, McLean PJ, Hyman BT. Hashimoto T, et al. Among authors: fan z. J Biol Chem. 2011 Aug 5;286(31):27081-91. doi: 10.1074/jbc.M111.257378. Epub 2011 Jun 7. J Biol Chem. 2011. PMID: 21652708 Free PMC article.

7

Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease.

DaRocha-Souto B, Coma M, Pérez-Nievas BG, Scotton TC, Siao M, Sánchez-Ferrer P, Hashimoto T, Fan Z, Hudry E, Barroeta I, Serenó L, Rodríguez M, Sánchez MB, Hyman BT, Gómez-Isla T. DaRocha-Souto B, et al. Among authors: fan z. Neurobiol Dis. 2012 Jan;45(1):425-37. doi: 10.1016/j.nbd.2011.09.002. Epub 2011 Sep 13. Neurobiol Dis. 2012. PMID: 21945540 Free PMC article.

8

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein.

Ebrahimi-Fakhari D, Cantuti-Castelvetri I, Fan Z, Rockenstein E, Masliah E, Hyman BT, McLean PJ, Unni VK. Ebrahimi-Fakhari D, et al. Among authors: fan z. J Neurosci. 2011 Oct 12;31(41):14508-20. doi: 10.1523/JNEUROSCI.1560-11.2011. J Neurosci. 2011. PMID: 21994367 Free PMC article.

9

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease.

Hudry E, Wu HY, Arbel-Ornath M, Hashimoto T, Matsouaka R, Fan Z, Spires-Jones TL, Betensky RA, Bacskai BJ, Hyman BT. Hudry E, et al. Among authors: fan z. J Neurosci. 2012 Feb 29;32(9):3176-92. doi: 10.1523/JNEUROSCI.6439-11.2012. J Neurosci. 2012. PMID: 22378890 Free PMC article.

10

Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-β revealed by a novel fluorescence resonance energy transfer assay.

Wu HY, Hudry E, Hashimoto T, Uemura K, Fan ZY, Berezovska O, Grosskreutz CL, Bacskai BJ, Hyman BT. Wu HY, et al. J Neurosci. 2012 Apr 11;32(15):5298-309. doi: 10.1523/JNEUROSCI.0227-12.2012. J Neurosci. 2012. PMID: 22496575 Free PMC article.

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