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RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.
Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP. Houles T, et al. Among authors: lavoie g. Cancer Res. 2018 May 1;78(9):2191-2204. doi: 10.1158/0008-5472.CAN-17-2215. Epub 2018 Feb 12. Cancer Res. 2018. PMID: 29440170
RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth.
Romeo Y, Moreau J, Zindy PJ, Saba-El-Leil M, Lavoie G, Dandachi F, Baptissart M, Borden KLB, Meloche S, Roux PP. Romeo Y, et al. Among authors: lavoie g. Oncogene. 2013 Jun 13;32(24):2917-2926. doi: 10.1038/onc.2012.312. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797077 Free PMC article.
Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
Zhang X, Lavoie G, Fort L, Huttlin EL, Tcherkezian J, Galan JA, Gu H, Gygi SP, Carreno S, Roux PP. Zhang X, et al. Among authors: lavoie g. Mol Cell Biol. 2013 Apr;33(8):1657-70. doi: 10.1128/MCB.01353-12. Epub 2013 Feb 11. Mol Cell Biol. 2013. PMID: 23401857 Free PMC article.
Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3.
Galan JA, Geraghty KM, Lavoie G, Kanshin E, Tcherkezian J, Calabrese V, Jeschke GR, Turk BE, Ballif BA, Blenis J, Thibault P, Roux PP. Galan JA, et al. Among authors: lavoie g. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2918-27. doi: 10.1073/pnas.1405601111. Epub 2014 Jul 7. Proc Natl Acad Sci U S A. 2014. PMID: 25002506 Free PMC article.
Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children.
de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL. de Smith AJ, et al. Among authors: lavoie g. Genes Chromosomes Cancer. 2019 Oct;58(10):723-730. doi: 10.1002/gcc.22765. Epub 2019 May 27. Genes Chromosomes Cancer. 2019. PMID: 31102422 Free PMC article.
86 results