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hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Pellicano F, Park L, Hopcroft LEM, Shah MM, Jackson L, Scott MT, Clarke CJ, Sinclair A, Abraham SA, Hair A, Helgason GV, Aspinall-O'Dea M, Bhatia R, Leone G, Kranc KR, Whetton AD, Holyoake TL. Pellicano F, et al. Among authors: shah mm. Blood. 2018 Apr 5;131(14):1532-1544. doi: 10.1182/blood-2017-05-783845. Epub 2018 Feb 5. Blood. 2018. PMID: 29437554 Free PMC article.
CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.
Sinclair A, Park L, Shah M, Drotar M, Calaminus S, Hopcroft LE, Kinstrie R, Guitart AV, Dunn K, Abraham SA, Sansom O, Michie AM, Machesky L, Kranc KR, Graham GJ, Pellicano F, Holyoake TL. Sinclair A, et al. Blood. 2016 Jul 21;128(3):371-83. doi: 10.1182/blood-2015-08-661785. Epub 2016 May 24. Blood. 2016. PMID: 27222476 Free PMC article.
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
Abraham A, Qiu S, Chacko BK, Li H, Paterson A, He J, Agarwal P, Shah M, Welner R, Darley-Usmar VM, Bhatia R. Abraham A, et al. J Clin Invest. 2019 Jun 10;129(7):2685-2701. doi: 10.1172/JCI127080. eCollection 2019 Jun 10. J Clin Invest. 2019. PMID: 31180336 Free PMC article.
A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells.
von Palffy S, Landberg N, Sandén C, Zacharaki D, Shah M, Nakamichi N, Hansen N, Askmyr M, Lilljebjörn H, Rissler M, Karlsson C, Scheding S, Richter J, Eaves CJ, Bhatia R, Järås M, Fioretos T. von Palffy S, et al. Haematologica. 2020 Aug;105(8):2095-2104. doi: 10.3324/haematol.2019.220434. Epub 2019 Oct 3. Haematologica. 2020. PMID: 31582541 Free PMC article.
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia.
Ramakrishnan R, Peña-Martínez P, Agarwal P, Rodriguez-Zabala M, Chapellier M, Högberg C, Eriksson M, Yudovich D, Shah M, Ehinger M, Nilsson B, Larsson J, Hagström-Andersson A, Ebert BL, Bhatia R, Järås M. Ramakrishnan R, et al. Cell Rep. 2020 May 26;31(8):107684. doi: 10.1016/j.celrep.2020.107684. Cell Rep. 2020. PMID: 32460032 Free PMC article.
385 results