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ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization.
Li J, Xie J, Liu S, Li X, Zhang D, Wang X, Jiang J, Hu W, Zhang Y, Jin B, Zhuang R, Yin W. Li J, et al. Among authors: wang x. FASEB J. 2018 Sep;32(9):5162-5173. doi: 10.1096/fj.201701449R. Epub 2018 Apr 25. FASEB J. 2018. PMID: 29694248
In summary, ADAR1 modulates macrophage M2 polarization via the ADAR1-miR-21-Foxo1-IL-10 axis, thereby suppressing allogeneic graft rejection.-Li, J., Xie, J., Liu, S., Li, X., Zhang, D., Wang, X., Jiang, J., Hu, W., Zhang, Y., Jin, B., Zhuang, R., Yin, W. ...
In summary, ADAR1 modulates macrophage M2 polarization via the ADAR1-miR-21-Foxo1-IL-10 axis, thereby suppressing allogeneic graft rejection …
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