Guo T - Search Results

1

A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.

Kagoya Y, Tanaka S, Guo T, Anczurowski M, Wang CH, Saso K, Butler MO, Minden MD, Hirano N. Kagoya Y, et al. Among authors: guo t. Nat Med. 2018 Mar;24(3):352-359. doi: 10.1038/nm.4478. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400710 Free PMC article.

2

Specific roles of each TCR hemichain in generating functional chain-centric TCR.

Nakatsugawa M, Yamashita Y, Ochi T, Tanaka S, Chamoto K, Guo T, Butler MO, Hirano N. Nakatsugawa M, et al. Among authors: guo t. J Immunol. 2015 Apr 1;194(7):3487-500. doi: 10.4049/jimmunol.1401717. Epub 2015 Feb 20. J Immunol. 2015. PMID: 25710913 Free PMC article.

3

Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy.

Ochi T, Nakatsugawa M, Chamoto K, Tanaka S, Yamashita Y, Guo T, Fujiwara H, Yasukawa M, Butler MO, Hirano N. Ochi T, et al. Among authors: guo t. Cancer Immunol Res. 2015 Sep;3(9):1070-81. doi: 10.1158/2326-6066.CIR-14-0222. Epub 2015 May 5. Cancer Immunol Res. 2015. PMID: 25943533 Free PMC article.

4

Adoptive T Cell Therapy Targeting CD1 and MR1.

Guo T, Chamoto K, Hirano N. Guo T, et al. Front Immunol. 2015 May 20;6:247. doi: 10.3389/fimmu.2015.00247. eCollection 2015. Front Immunol. 2015. PMID: 26052329 Free PMC article. Review.

5

CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.

Chamoto K, Guo T, Imataki O, Tanaka M, Nakatsugawa M, Ochi T, Yamashita Y, Saito AM, Saito TI, Butler MO, Hirano N. Chamoto K, et al. Among authors: guo t. J Autoimmun. 2016 Apr;68:39-51. doi: 10.1016/j.jaut.2015.12.005. Epub 2015 Dec 31. J Autoimmun. 2016. PMID: 26748722 Free PMC article.

6

CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells.

Nakatsugawa M, Rahman MA, Yamashita Y, Ochi T, Wnuk P, Tanaka S, Chamoto K, Kagoya Y, Saso K, Guo T, Anczurowski M, Butler MO, Hirano N. Nakatsugawa M, et al. Among authors: guo t. Sci Rep. 2016 Mar 31;6:23821. doi: 10.1038/srep23821. Sci Rep. 2016. PMID: 27030642 Free PMC article.

7

Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors.

Guo T, Chamoto K, Nakatsugawa M, Ochi T, Yamashita Y, Anczurowski M, Butler MO, Hirano N. Guo T, et al. PLoS One. 2016 May 23;11(5):e0156114. doi: 10.1371/journal.pone.0156114. eCollection 2016. PLoS One. 2016. PMID: 27213277 Free PMC article.

8

BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.

Kagoya Y, Nakatsugawa M, Yamashita Y, Ochi T, Guo T, Anczurowski M, Saso K, Butler MO, Arrowsmith CH, Hirano N. Kagoya Y, et al. Among authors: guo t. J Clin Invest. 2016 Sep 1;126(9):3479-94. doi: 10.1172/JCI86437. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548527 Free PMC article.

9

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain.

Guo T, Ochi T, Nakatsugawa M, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Hirano N. Guo T, et al. J Vis Exp. 2016 Oct 25;(116):54697. doi: 10.3791/54697. J Vis Exp. 2016. PMID: 27805596 Free PMC article.

10

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N. Chamoto K, et al. Among authors: guo t. J Immunol. 2017 Feb 1;198(3):1056-1065. doi: 10.4049/jimmunol.1601556. Epub 2016 Dec 21. J Immunol. 2017. PMID: 28003379 Free PMC article.

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