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Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes.
Andreasen L, Ahlberg G, Tang C, Andreasen C, Hartmann JP, Tfelt-Hansen J, Behr ER, Pehrson S, Haunsø S, LuCamp, Weeke PE, Jespersen T, Olesen MS, Svendsen JH. Andreasen L, et al. Among authors: andreasen c. Eur J Hum Genet. 2018 May;26(5):660-668. doi: 10.1038/s41431-017-0092-0. Epub 2018 Feb 2. Eur J Hum Genet. 2018. PMID: 29396561 Free PMC article.
Brugada syndrome risk loci seem protective against atrial fibrillation.
Andreasen L, Nielsen JB, Darkner S, Christophersen IE, Jabbari J, Refsgaard L, Thiis JJ, Sajadieh A, Tveit A, Haunsø S, Svendsen JH, Schmitt N, Olesen MS. Andreasen L, et al. Eur J Hum Genet. 2014 Dec;22(12):1357-61. doi: 10.1038/ejhg.2014.46. Epub 2014 Mar 26. Eur J Hum Genet. 2014. PMID: 24667784 Free PMC article.
Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality.
Ghouse J, Have CT, Skov MW, Andreasen L, Ahlberg G, Nielsen JB, Skaaby T, Olesen SP, Grarup N, Linneberg A, Pedersen O, Vestergaard H, Haunsø S, Svendsen JH, Hansen T, Kanters JK, Olesen MS. Ghouse J, et al. Among authors: andreasen l. Genet Med. 2017 May;19(5):521-528. doi: 10.1038/gim.2016.151. Epub 2016 Oct 6. Genet Med. 2017. PMID: 27711072 Free article.
Deep sequencing of atrial fibrillation patients with mitral valve regurgitation shows no evidence of mosaicism but reveals novel rare germline variants.
Gregers E, Ahlberg G, Christensen T, Jabbari J, Larsen KO, Herfelt CB, Henningsen KM, Andreasen L, Thiis JJ, Lund J, Holme S, Haunsø S, Bentzen BH, Schmitt N, Svendsen JH, Olesen MS. Gregers E, et al. Among authors: andreasen l. Heart Rhythm. 2017 Oct;14(10):1531-1538. doi: 10.1016/j.hrthm.2017.05.027. Epub 2017 May 24. Heart Rhythm. 2017. PMID: 28549997
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation.
Ahlberg G, Refsgaard L, Lundegaard PR, Andreasen L, Ranthe MF, Linscheid N, Nielsen JB, Melbye M, Haunsø S, Sajadieh A, Camp L, Olesen SP, Rasmussen S, Lundby A, Ellinor PT, Holst AG, Svendsen JH, Olesen MS. Ahlberg G, et al. Among authors: andreasen l. Nat Commun. 2018 Oct 17;9(1):4316. doi: 10.1038/s41467-018-06618-y. Nat Commun. 2018. PMID: 30333491 Free PMC article.
111 results