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Site-specific protein modifications through pyrroline-carboxy-lysine residues.
Ou W, Uno T, Chiu HP, Grünewald J, Cellitti SE, Crossgrove T, Hao X, Fan Q, Quinn LL, Patterson P, Okach L, Jones DH, Lesley SA, Brock A, Geierstanger BH. Ou W, et al. Among authors: uno t. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10437-42. doi: 10.1073/pnas.1105197108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670250 Free PMC article.
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.
Cellitti SE, Jones DH, Lagpacan L, Hao X, Zhang Q, Hu H, Brittain SM, Brinker A, Caldwell J, Bursulaya B, Spraggon G, Brock A, Ryu Y, Uno T, Schultz PG, Geierstanger BH. Cellitti SE, et al. Among authors: uno t. J Am Chem Soc. 2008 Jul 23;130(29):9268-81. doi: 10.1021/ja801602q. Epub 2008 Jun 25. J Am Chem Soc. 2008. PMID: 18576636 Free PMC article.
Site-specific labeling of proteins with NMR-active unnatural amino acids.
Jones DH, Cellitti SE, Hao X, Zhang Q, Jahnz M, Summerer D, Schultz PG, Uno T, Geierstanger BH. Jones DH, et al. Among authors: uno t. J Biomol NMR. 2010 Jan;46(1):89-100. doi: 10.1007/s10858-009-9365-4. Epub 2009 Aug 9. J Biomol NMR. 2010. PMID: 19669620 Review.
Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Phosphopantetheinyl Transferases.
Grünewald J, Klock HE, Cellitti SE, Bursulaya B, McMullan D, Jones DH, Chiu HP, Wang X, Patterson P, Zhou H, Vance J, Nigoghossian E, Tong H, Daniel D, Mallet W, Ou W, Uno T, Brock A, Lesley SA, Geierstanger BH. Grünewald J, et al. Among authors: uno t. Bioconjug Chem. 2015 Dec 16;26(12):2554-62. doi: 10.1021/acs.bioconjchem.5b00558. Epub 2015 Dec 4. Bioconjug Chem. 2015. PMID: 26588668
Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Michellys PY, Chen B, Jiang T, Jin Y, Lu W, Marsilje TH, Pei W, Uno T, Zhu X, Wu B, Nguyen TN, Bursulaya B, Lee C, Li N, Kim S, Tuntland T, Liu B, Sun F, Steffy A, Hood T. Michellys PY, et al. Among authors: uno t. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1090-1096. doi: 10.1016/j.bmcl.2015.11.049. Epub 2015 Nov 17. Bioorg Med Chem Lett. 2016. PMID: 26750252
1,059 results