Nakao R - Search Results

1

Development of [ Carbonyl-¹¹C]AZ13198083, a Novel Histamine Type-3 Receptor Radioligand with Favorable Kinetics.

Dahl K, Nakao R, Amini N, Moein MM, Finnema S, Malmquist J, Varnäs K, Schou M. Dahl K, et al. Among authors: nakao r. ACS Chem Neurosci. 2018 May 16;9(5):906-911. doi: 10.1021/acschemneuro.7b00493. Epub 2018 Jan 30. ACS Chem Neurosci. 2018. PMID: 29359917

2

Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor.

Schou M, Varnäs K, Jureus A, Ahlgren C, Malmquist J, Häggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnström P, Finnema SJ, Nakao R, Amini N, Takano A, Farde L. Schou M, et al. Among authors: nakao r. ACS Chem Neurosci. 2016 Feb 17;7(2):177-84. doi: 10.1021/acschemneuro.5b00268. Epub 2015 Nov 30. ACS Chem Neurosci. 2016. PMID: 26529287

3

Rapid and sensitive measurement of PET radioligands in plasma by fast liquid chromatography/radiometric detection.

Nakao R, Schou M, Halldin C. Nakao R, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 May 1;895-896:116-22. doi: 10.1016/j.jchromb.2012.03.028. Epub 2012 Mar 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22494928

4

Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.

Amini N, Nakao R, Schou M, Halldin C. Amini N, et al. Among authors: nakao r. Anal Bioanal Chem. 2013 Feb;405(4):1303-10. doi: 10.1007/s00216-012-6541-2. Epub 2012 Nov 21. Anal Bioanal Chem. 2013. PMID: 23180082

5

Simultaneous determination of protein-free and total positron emission tomography radioligand concentrations in plasma using high-performance frontal analysis followed by mixed micellar liquid chromatography: application to [11C]PBR28 in human plasma.

Nakao R, Amini N, Halldin C. Nakao R, et al. Anal Chem. 2013 Sep 17;85(18):8728-34. doi: 10.1021/ac401742v. Epub 2013 Sep 5. Anal Chem. 2013. PMID: 23978238

6

Characterization of [(11)C]Cimbi-36 as an agonist PET radioligand for the 5-HT(2A) and 5-HT(2C) receptors in the nonhuman primate brain.

Finnema SJ, Stepanov V, Ettrup A, Nakao R, Amini N, Svedberg M, Lehmann C, Hansen M, Knudsen GM, Halldin C. Finnema SJ, et al. Among authors: nakao r. Neuroimage. 2014 Jan 1;84:342-53. doi: 10.1016/j.neuroimage.2013.08.035. Epub 2013 Aug 28. Neuroimage. 2014. PMID: 23994452

7

Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates.

Schou M, Varnäs K, Sandell J, Johnström P, Cselenyi Z, Svensson S, Nakao R, Amini N, Bergman L, Sumic A, Gulyas B, Lindström-Böö E, Halldin C, Farde L. Schou M, et al. Among authors: nakao r. Mol Imaging Biol. 2014 Apr;16(2):173-9. doi: 10.1007/s11307-013-0666-3. Mol Imaging Biol. 2014. PMID: 24002613

8

Determination of plasma protein binding of positron emission tomography radioligands by high-performance frontal analysis.

Amini N, Nakao R, Schou M, Halldin C. Amini N, et al. Among authors: nakao r. J Pharm Biomed Anal. 2014 Sep;98:140-3. doi: 10.1016/j.jpba.2014.05.024. Epub 2014 May 27. J Pharm Biomed Anal. 2014. PMID: 24922085

9

Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain.

Finnema SJ, Hughes ZA, Haaparanta-Solin M, Stepanov V, Nakao R, Varnäs K, Varrone A, Arponen E, Marjamäki P, Pohjanoksa K, Vuorilehto L, Babalola PA, Solin O, Grimwood S, Sallinen J, Farde L, Scheinin M, Halldin C. Finnema SJ, et al. Among authors: nakao r. Int J Neuropsychopharmacol. 2014 Dec 13;18(3):pyu081. doi: 10.1093/ijnp/pyu081. Int J Neuropsychopharmacol. 2014. PMID: 25522417 Free PMC article.

10

Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates.

Schou M, Varnäs K, Lundquist S, Nakao R, Amini N, Takano A, Finnema SJ, Halldin C, Farde L. Schou M, et al. Among authors: nakao r. Int J Neuropsychopharmacol. 2015 Mar 26;18(10):pyv036. doi: 10.1093/ijnp/pyv036. Int J Neuropsychopharmacol. 2015. PMID: 25813017 Free PMC article.

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